Search results
Results from the WOW.Com Content Network
Function: An enzyme that is produced by animals that forms part of the innate immune system and is abundant in the secretions of saliva, human milk, tears, and mucus. It functions as an antimicrobial agent by splitting the peptidoglycan component of bacterial cell walls, which then leads to cell death.
Enzyme denaturation is normally linked to temperatures above a species' normal level; as a result, enzymes from bacteria living in volcanic environments such as hot springs are prized by industrial users for their ability to function at high temperatures, allowing enzyme-catalysed reactions to be operated at a very high rate.
Enzymes appear in the subcategory Category:Enzymes by function according to the EC number classification: . EC 1 Oxidoreductases: catalyze oxidation/reduction reactions; EC 2 Transferases: transfer a functional group (e.g. a methyl or phosphate group)
FMO3 is the primary enzyme in humans which catalyzes the N-oxidation of trimethylamine into trimethylamine N-oxide; [8] [10] FMO1 also does this, but to a much lesser extent than FMO3. [13] [14] Genetic deficiencies of the FMO3 enzyme cause primary trimethylaminuria, also known as "fish odor syndrome".
Cytochrome P450 enzymes also function to metabolize potentially toxic compounds, including drugs and products of endogenous metabolism such as bilirubin, principally in the liver. The Human Genome Project has identified 57 human genes coding for the various cytochrome P450 enzymes. [5]
In humans, these genes are located on chromosomes 11 and 12 and encode two different homologous enzymes TPH1 and TPH2 (sequence identity 71%). [ 6 ] TPH1 is mostly expressed in tissues that express serotonin (a neurotransmitter) in the periphery ( skin , gut , pineal gland ) but it is also expressed in the central nervous system.
Carbonic anhydrase IX (CA9/CA IX) is an enzyme that in humans is encoded by the CA9 gene. [5] [6] [7] It is one of the 14 carbonic anhydrase isoforms found in humans and is a transmembrane dimeric metalloenzyme with an extracellular active site that facilitates acid secretion in the gastrointestinal tract. [8]
29102 14000 Ensembl ENSG00000113360 ENSMUSG00000022191 UniProt Q9NRR4 Q5HZJ0 RefSeq (mRNA) NM_001100412 NM_013235 NM_001382508 NM_001130149 NM_026799 RefSeq (protein) NP_001093882 NP_037367 NP_001369437 NP_001123621 NP_081075 Location (UCSC) Chr 5: 31.4 – 31.53 Mb Chr 15: 12.82 – 12.94 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Drosha is a Class 2 ribonuclease III enzyme ...