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  2. Spinal muscular atrophy - Wikipedia

    en.wikipedia.org/wiki/Spinal_muscular_atrophy

    SMA 4 (Adult onset) Adulthood This denotes the adult-onset form, sometimes also classified as a late-onset SMA type 3. It occurs in approx. 5% of patients and usually manifests in the third or fourth decade of life. The symptoms consist of gradual weakening of leg muscles, which frequently makes it necessary for the patient to use walking aids.

  3. Spinal muscular atrophies - Wikipedia

    en.wikipedia.org/wiki/Spinal_muscular_atrophies

    Spinal muscular atrophies (SMAs) are a genetically and clinically heterogeneous group of rare debilitating disorders characterised by the degeneration of lower motor neurons (neuronal cells situated in the anterior horn of the spinal cord) and subsequent atrophy (wasting) of various muscle groups in the body. [1]

  4. Spinal and bulbar muscular atrophy - Wikipedia

    en.wikipedia.org/wiki/Spinal_and_bulbar_muscular...

    Spinal and bulbar muscular atrophy (SBMA), popularly known as Kennedy's disease, is a rare, adult-onset, X-linked recessive lower motor neuron disease caused by trinucleotide CAG repeat expansions in exon 1 of the androgen receptor (AR) gene, which results in both loss of AR function and toxic gain of function.

  5. List of neuromuscular disorders - Wikipedia

    en.wikipedia.org/wiki/List_of_neuromuscular...

    Late adult-onset type 1; ... Spinal muscular atrophy with respiratory distress type 1; ... congenital (trauma, Mobius syndrome, cardiofacial syndrome)

  6. Superior mesenteric artery syndrome - Wikipedia

    en.wikipedia.org/wiki/Superior_mesenteric_artery...

    SMA syndrome is also known as Wilkie's syndrome, cast syndrome, mesenteric root syndrome, chronic duodenal ileus and intermittent arterio-mesenteric occlusion. [3] It is distinct from nutcracker syndrome , which is the entrapment of the left renal vein between the AA and the SMA, although it is possible to be diagnosed with both conditions.

  7. Distal hereditary motor neuronopathies - Wikipedia

    en.wikipedia.org/wiki/Distal_hereditary_motor...

    Distal hereditary motor neuronopathies (distal HMN, dHMN), sometimes also called distal hereditary motor neuropathies, are a genetically and clinically heterogeneous group of motor neuron diseases that result from genetic mutations in various genes and are characterized by degeneration and loss of motor neuron cells in the anterior horn of the spinal cord and subsequent muscle atrophy.

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  9. Jokela type spinal muscular atrophy - Wikipedia

    en.wikipedia.org/wiki/Jokela_type_spinal...

    The disease is slowly progressive with adult onset and results in weakness and mild muscle atrophy. [ 1 ] [ 3 ] The disease does not affect life expectancy . [ 1 ] However, it is difficult to differentiate the disease from a more fatal amyotrophic lateral sclerosis in diagnosis.

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