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This topic will review treatment regimens for H. pylori. The bacteriology, epidemiology, and diagnostic tests for H. pylori infection are discussed elsewhere.
H. pylori treatment helps to heal the ulcer, lowers the risk that the ulcer will return, and lowers the risk of bleeding from the ulcer. H. pylori treatment usually includes several medicines. At least two of the medicines are antibiotics that help to kill the bacteria.
This topic review will provide an overview of screening, diagnosis, and management of H. pylori infection in children and adolescents, highlighting differences in management compared with adults. Evaluation and management of H. pylori in adults are discussed separately.
A suggested approach to the selection of antibiotics for initial treatment of H. pylori infection is outlined in the algorithm (algorithm 1 and table 1). (See 'Clarithromycin-based therapy' below.) (Related Pathway(s): Helicobacter pylori: Initial treatment for adults .)
H. pylori treatment helps to heal the ulcer, lowers the risk that the ulcer will return, and lowers the risk of bleeding from the ulcer. H. pylori treatment usually includes several medicines … ›
Testing for H. pylori should be performed only if the clinician plans to offer treatment for positive results. Indications for testing include : Gastric marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)
Treatment regimens for H. pylori are discussed in detail, separately. (See "Indications and diagnostic tests for Helicobacter pylori infection in adults" and "Treatment regimens for Helicobacter pylori in adults".) Discontinue nonsteroidal anti-inflammatory drugs (NSAIDs) — Patients with peptic ulcers should be advised to avoid NSAIDs. NSAIDs ...
Treatment approaches commonly include conservative measures (dietary and lifestyle modifications) and/or medication(s). Patients who fail to respond to outpatient medical management may require hospitalization for parenteral fluids and medications.
Treatment options in patients who test negative for H. pylori or remain symptomatic after its eradication and have inadequate response to a proton pump inhibitor include a tricyclic agent and prokinetics.
Explore the mechanism of action, pharmacology, and side effects of antiulcer medications like esomeprazole on UpToDate.