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Scurvy is a deficiency disease (state of malnutrition) resulting from a lack of vitamin C (ascorbic acid). [1] Early symptoms of deficiency include weakness, fatigue, and sore arms and legs. [1] [2] Without treatment, decreased red blood cells, gum disease, changes to hair, and bleeding from the skin may occur.
The design for a medical study in 1743 that was never carried out may have inspired James Lind’s groundbreaking clinical trial that determined the treatment for scurvy.
Scurvy is a disease caused by a vitamin C deficiency, but in Lind's day, the concept of vitamins was unknown. Vitamin C is necessary for healthy connective tissue. In 1740 the catastrophic result of then-Commodore George Anson's circumnavigation attracted much attention in Europe; out of 1900 men, 1400 died, most of them allegedly from scurvy ...
Lemon juice, recommended by James Lind in his Treatise on the Scurvy of 1754, in the end prevailed as a treatment; but Macbride's brother John, who was commander of HMS Jason, made an experiment with the cure in a voyage of 1765–7, and the ship's surgeon, Alexander Young, sent his journal to Macbride, who published it as an appendix to the ...
Vitamin C has a definitive role in treating scurvy, which is a disease caused by vitamin C deficiency. Beyond that, a role for vitamin C as prevention or treatment for various diseases is disputed, with reviews often reporting
The Sick and Hurt Commissioners are credited with the eradication of scurvy from the Royal Navy by putting to use the ideas of Johann Bachstrom and James Lind, who believed lemons, limes or other citrus fruits could help prevent the disease. In his 1734 book Observationes circa scorbutum ("Observations on Scurvy"), Bachstrom wrote that:
Theodor Christian Brun Frølich (29 September 1870 – 14 August 1947) was a Norwegian physician and Professor of Pediatrics at the University of Oslo.In 1938 he was nominated for the Nobel Prize in Physiology or Medicine for his pioneering contributions to the study of the treatment of Scurvy and to the development of Vitamin C.
Alternative Medicine on Trial (North American title: Trick or Treatment: The Undeniable Facts about Alternative Medicine) [1] is a 2008 book by Simon Singh and Edzard Ernst. [ 2 ] [ 3 ] [ 4 ] The book evaluates the scientific evidence for alternative medicines such as acupuncture , homeopathy , herbal medicine , and chiropractic , [ 2 ] and ...