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I use it on my feet for a month 2 times a day for precancerous skin. After the treatment the skin remains blotchy, red, scabby, dry, and my feet feel like they are on fire.
This video takes you along on my journey of 24 days using the Fluorouracil (also known as Fluoroplex, Tolak, Efudex, Carac, and Adrucil) as a topical cream chemotherapy treatment. It can treat rough, raised areas of heavily sun-exposed skin (actinic or solar keratoses).
Fluorouracil (5-FU) is a skin cream or solution that treats skin cancer. It’s a chemotherapy agent that destroys cancer cells. Follow the instructions on the label to safely apply this cream or solution on your skin.
A recent randomized control trial of 624 patients comparing 5% fluorouracil cream, 5% imiquimod cream, methyl aminolevulinate photodynamic therapy (MAL-PDT) and 0.015% ingenol mebutate gel demonstrated that 5% fluorouracil was significantly more effective for the treatment of multiple actinic keratoses. 10
For topical dosage form (cream and solution): For actinic or solar keratosis: Adults—Apply to the affected area 2 times a day for 2 to 4 weeks. Children—Use and dose must be determined by your doctor. For superficial basal cell carcinomas: Adults—Apply to the affected area 2 times a day for 3 to 6 weeks.
Follow up after fluorouracil treatment. After you have been instructed to stop using the fluorouracil cream, you may be prescribed a specific moisturiser or mild topical steroid to help to heal the treated area.
Tips for how to use Efudex. While instructions for application and treatment times can vary greatly from one patient to the next depending upon the damage being addressed, there are some general rules to keep in mind as you set out on your own Efudex journey.
It is used to treat a precancerous skin problem called actinic keratosis. It is used to treat a type of skin cancer called basal cell carcinoma. Only the 5% strength is for use to treat basal cell carcinoma.
For basal cell carcinoma, dermatologists usually recommend applying 5% fluorouracil cream in an amount sufficient to cover the lesions two times per day for three to six weeks. However, sometimes therapy lasts as long as 10 to 12 weeks before the lesions disappear.
It is used to treat a precancerous skin problem called actinic keratosis. It is used to treat a type of skin cancer called basal cell carcinoma. Only the 5% strength is for use to treat basal cell carcinoma.