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Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety, obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [1]
The symptoms of anxiety and depression disorders can be very similar. A diagnosis of mixed anxiety–depressive disorder as opposed to a diagnosis of depression or an anxiety disorder can be difficult. Due to this, it has long been a struggle to find a singular set of criteria to use in the diagnosis of mixed-anxiety depressive disorder. [3]
Guanfacine is also used off-label to treat tic disorders, anxiety disorders such as generalized anxiety disorder, and PTSD. [ 24 ] [ 15 ] Guanfacine and other α 2A -adrenergic receptor agonists have anxiolytic -like action, [ 25 ] thereby reducing the emotional responses of the amygdala , and strengthening prefrontal cortical regulation of ...
The Canadian Network for Mood and Anxiety Treatments (CANMAT) recommends esketamine as a third-line treatment for depression. [ 26 ] A Cochrane review of randomized controlled trials in adults with unipolar major depressive disorder , [ 19 ] found that when compared with placebo, people treated with either ketamine or esketamine experienced ...
The main indication for SSRIs is major depressive disorder; however, they are frequently prescribed for anxiety disorders, such as social anxiety disorder, generalized anxiety disorder, panic disorder, obsessive–compulsive disorder (OCD), eating disorders, chronic pain, and, in some cases, for posttraumatic stress disorder (PTSD).
Etifoxine, sold under the trade name Stresam among others, is a nonbenzodiazepine anxiolytic agent, primarily indicated for short-term management of adjustment disorder, specifically instances of situational depression accompanied by anxiety, such as stress-induced anxiety. [2] [6] Administration is by mouth. [7]
Vortioxetine appears to work in depressed patients with anxiety. [30] Vortioxetine is also used off-label for anxiety. [31] A 2016 review found it was not useful in generalized anxiety disorder at 2.5, 5, and 10 mg doses (15 and 20 mg doses were not tested). [32]
This medicine is also sometimes used for neuropathic pain, attention deficit hyperactivity disorder (ADHD), smoking cessation and anxiety. [ 7 ] [ 8 ] Its use for young people with depression and other psychiatric disorders may be limited due to increased suicidality in the 18–24 population initiating treatment. [ 8 ]