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Xanthelasma is a sharply demarcated yellowish deposit of cholesterol underneath the skin. [1] It usually occurs on or around the eyelids ( xanthelasma palpebrarum , abbreviated XP). [ 1 ] [ 2 ] While they are neither harmful to the skin nor painful , these minor growths may be disfiguring and can be removed. [ 1 ]
A Hollenhorst plaque (also known as a retinal cholesterol embolus) is a cholesterol embolus that is seen in a blood vessel of the retina.It is usually found when a physician performs ophthalmoscopy, during which a plaque will appear as a small, bright crystal that is refractile (reflects the light from the ophthalmoscope) and yellow. [1]
A xanthelasma is a sharply demarcated yellowish collection of cholesterol underneath the skin, usually on or around the eyelids. Strictly, a xanthelasma is a distinct condition, being called a xanthoma only when becoming larger and nodular, assuming tumorous proportions. [3] Still, it is often classified simply as a subtype of xanthoma. [4]
Physical examination findings can help a physician make the diagnosis of FH. Tendon xanthomas are seen in 20-40% of individuals with FH and are pathognomonic for the condition. [9] A xanthelasma or corneal arcus may also be seen. These common signs are supportive of the diagnosis, but are non-specific findings. [9]
List of cutaneous conditions associated with increased risk of nonmelanoma skin cancer; List of cutaneous conditions associated with internal malignancy; List of cutaneous conditions caused by mutations in keratins; List of cutaneous conditions caused by problems with junctional proteins; List of dental abnormalities associated with cutaneous ...
Touton giant cells are a type of multinucleated giant cell observed in a myriad of pathological disorders and conditions. Specifically, Touton giant cells are found in lipid-rich lesions such as those of fat necrosis, xanthoma, xanthelasma and xanthogranulomas. Touton giant cells are also referred to as xanthelasmatic cells due to the fact they ...
Antiphospholipid syndrome is known for causing arterial or venous blood clots, in any organ system, and pregnancy-related complications.While blood clots and pregnancy complications are the most common and diagnostic symptoms associated with APS, other organs and body parts may be affected like platelet levels, heart, kidneys, brain, and skin.
Xanthelasma and corneal arcus are less common. Decreased range of motion with possible redness, swelling, and warmth of joints due to arthritis may be present. In addition, sitosterolemia patients may develop hemolytic episodes and splenomegaly. Untreated, the condition causes a significant increase in morbidity and mortality.