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Dobutamine is a direct-acting agent whose primary activity results from stimulation of the β 1-adrenoceptors of the heart, increasing contractility and cardiac output. Since it does not act on dopamine receptors to inhibit the release of norepinephrine (another α 1 agonist), dobutamine is less prone to induce hypertension than is dopamine.
Cardiotonic agents, also known as cardiac inotropes or stimulants, have a positive impact on the myocardium (muscular layer of the heart) by enhancing its contractility. . Unlike general inotropes, these agents exhibit a higher level of specificity as they selectively target the myocar
Dobutamine – The effects of beta-agonists such as dobutamine can be reversed by administering beta-blockers such as propranolol. Regadenoson or dobutamine is often used in patients with severe reactive airway disease (asthma or COPD) as adenosine and dipyridamole can cause acute exacerbation of these conditions. If the patient's asthma is ...
Onset may be rapid (acute) or more gradual (subacute). [10] [2] Signs of cardiac tamponade typically include those of cardiogenic shock including shortness of breath, weakness, lightheadedness, cough [1] and those of Beck's triad e.g. jugular vein distention, quiet heart sounds and hypotension.
Hypotension, also known as low blood pressure, is a cardiovascular condition characterized by abnormally reduced blood pressure. [1] Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood [2] and is indicated by two numbers, the systolic blood pressure (the top number) and the diastolic blood pressure (the bottom number), which are the ...
Atrial fibrillation (AF, AFib or A-fib) is an abnormal heart rhythm (arrhythmia) characterized by rapid and irregular beating of the atrial chambers of the heart. [11] [12] It often begins as short periods of abnormal beating, which become longer or continuous over time. [4]
Enjoy a classic game of Hearts and watch out for the Queen of Spades!
Side effects of oral amiodarone at doses of 400 mg or higher include various pulmonary effects. [44] The most serious reaction is interstitial lung disease . Risk factors include high cumulative dose, more than 400 milligrams per day, duration over two months, increased age, and preexisting pulmonary disease.