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Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole insecticide class. [3] Fipronil disrupts the insect central nervous system by blocking the ligand-gated ion channel of the GABA A receptor (IRAC group 2B) and glutamate-gated chloride (GluCl) channels. This causes hyperexcitation of contaminated insects' nerves and muscles.
Chemical structure of fipronil, a common phenylpyrazole insecticide. Phenylpyrazole insecticides are a class of chemically-related broad-spectrum insecticides. [1] The chemical structures of these insecticides are characterized by a central pyrazole ring with a phenyl group attached to one of the nitrogen atoms of the pyrazole.
A comparison of 3 insecticides (selamectin, fipronil, imidacloprid) showed that selamectin reduced larval cat fleas ≥93.5% after 24 h at doses of ≥0.3 μg. In contrast, at 24 h neither fipronil nor imidacloprid reached 90% reduction, even at the highest doses tested (0.5 μg for fipronil and 5.0 μg for imidacloprid).
Pyriprole is a phenyl pyrazole derivative similar to fipronil. [citation needed] Although introduced (in the 2000s) and under patent protection it is a "classic" insecticide. [citation needed] [clarification needed] It is only approved in the EU and a few other countries for use on dogs. [citation needed] It is not approved for use on cats or ...
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A veterinarian's warning is an important public service announcement to all pet owners — especially people who have cats. Dr. Michele Forbes, DVM shared an update amid the news that the H5N1 ...
Cat communication falls under three main categories: murmuring, meowing, and aggressive. We all know what a meow sounds like, and you’ve probably heard the eerie warble that cats vocalize when ...
A single treatment with a topical formulation containing fipronil, (S)-methoprene, eprinomectin and praziquantel was shown to be efficient for the prevention of Otodectes cynotis infestation in cats. Methoprene is able to prevent eggs from hatching and stop mites from maturing; the rest are all parasite-killing drugs. [10]
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