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  2. Esomeprazole - Wikipedia

    en.wikipedia.org/wiki/Esomeprazole

    Esomeprazole's successful predecessor, omeprazole, is a mixture of two mirror-imaged molecules (esomeprazole which is the S-enantiomer, and R-omeprazole); critics said the company was trying to "evergreen" its omeprazole patent by patenting the pure esomeprazole and aggressively marketing to doctors that it is more effective than the mixture. [50]

  3. ATC code A02 - Wikipedia

    en.wikipedia.org/wiki/ATC_code_A02

    ATC code A02 Drugs for acid related disorders is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.

  4. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    Proton-pump inhibitors have largely superseded the H 2-receptor antagonists, a group of medications with similar effects but a different mode of action, and heavy use of antacids. [3] A potassium-competitive acid blocker (PCAB) revaprazan was marketed in Korea as an alternative to a PPI.

  5. Omeprazole - Wikipedia

    en.wikipedia.org/wiki/Omeprazole

    AstraZeneca also developed esomeprazole (Nexium) which is a eutomer, purely the (S)-enantiomer, rather than a racemate like omeprazole. [ medical citation needed ] Omeprazole undergoes a chiral shift in vivo which converts the inactive ( R )-enantiomer to the active ( S )-enantiomer, doubling the concentration of the active form. [ 59 ]

  6. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Esomeprazole is the (S)-(−)-enantiomer of omeprazole and provides higher bioavailability and improved efficacy, in terms of stomach acid control, over the (R)-(+)-enantiomer of omeprazole. In theory, by using pure esomeprazole the effects on the proton pump will be equal in all patients, eliminating the "poor metabolizer effect" of the ...

  7. A Doctor Explains Exactly What Happens To Your Brain During ...

    www.aol.com/doctor-explains-exactly-happens...

    Eating foods with magnesium and tyrosine, an amino acid, can boost dopamine production. Foods to try include chicken, almonds, apples, avocados, bananas, beets, chocolate, leafy green vegetables ...

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