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Loss of all four alpha-globin genes (total alpha-thalassemia) leads to severely anemic stillborn babies with small amounts of an abnormal hemoglobin composed of four gamma sub-units (Bart's Hemoglobin) Bastian–Bruns sign: Henry Charlton Bastian, Ludwig Bruns: neurology: spinal cord transection: loss of muscle tone and reflexes below lesion level
List of medical symptoms. Medical symptoms refer to the manifestations or indications of a disease or condition, perceived and complained about by the patient. [1] [2] Patients observe these symptoms and seek medical advice from healthcare professionals.
Signs and symptoms are not mutually exclusive, for example a subjective feeling of fever can be noted as sign by using a thermometer that registers a high reading. [ 7 ] Because many symptoms of cancer are gradual in onset and general in nature, cancer screening (also called cancer surveillance) is a key public health priority.
Fever is one of the most common medical signs. [2] It is part of about 30% of healthcare visits by children [ 2 ] and occurs in up to 75% of adults who are seriously sick. [ 11 ] While fever evolved as a defense mechanism, treating a fever does not appear to improve or worsen outcomes.
Diagnosis of continuous fever is usually based on the clinical signs and symptoms but some biological tests, chest X-ray and CT scan are also used. [2] Typhoid fever is an example of continuous fever and it shows a characteristic step-ladder pattern, a step-wise increase in temperature with a high plateau.
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Fever greater than 38 °C. Pel–Ebstein fever, the classic intermittent fever associated with Hodgkin disease, occurs at variable intervals of days to weeks and lasts for 1–2 weeks before resolving. However, fever associated with lymphoma can follow virtually any pattern. Drenching sweats, especially at night.
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