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Mayberg is known in particular for her work delineating abnormal brain function in patients with major depression using functional neuroimaging. [1] [2] This work led to the first pilot study of deep brain stimulation (DBS), a reversible method of selective modulation of a specific brain circuit, for patients with treatment-resistant depression ...
Deep brain stimulation (DBS) is a surgical procedure that implants a neurostimulator and electrodes which sends electrical impulses to specified targets in the brain responsible for movement control. The treatment is designed for a range of movement disorders such as Parkinson's disease, essential tremor, and dystonia, as well as for certain ...
D065908. [edit on Wikidata] Transcranial direct current stimulation (tDCS) is a form of neuromodulation that uses constant, low direct current delivered via electrodes on the head. It was originally developed to help patients with brain injuries or neuropsychiatric conditions such as major depressive disorder.
The subcallosal cingulate gyrus CG25 which consists of BA25 as well as parts of BA24 and BA32 has been implicated as playing an important role in major depression and has been the target of deep brain stimulation to treat the disorder. [6] One study found that BA25 is metabolically overactive in treatment-resistant depression. [7]
Biology of depression. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD), [ 1 ] and this has encouraged advocates of various theories that seek to identify a biochemical origin of the disease, as opposed to theories that emphasize psychological or situational causes.
Deep brain stimulation (DBS) has shown benefits for movement disorders such as Parkinson's disease, tremor and dystonia and other neuropsychiatric disorders such as depression, obsessive-compulsive disorder, Tourette syndrome, chronic pain and cluster headache. DBS can directly change the brain activity in a controlled manner and is hence used ...
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