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In Hashimoto's disease, immune-system cells lead to the death of the thyroid's hormone-producing cells. The disease usually results in a decline in hormone production (hypothyroidism). Although anyone can develop Hashimoto's disease, it's most common among middle-aged women.
Usually in Hashimoto's disease, the immune system produces an antibody to thyroid peroxidase (TPO), a protein that plays an important part in thyroid hormone production. Most people with Hashimoto's disease will have thyroid peroxidase (TPO) antibodies in their blood.
The most common cause of hypothyroidism is an autoimmune disease called Hashimoto's disease. Autoimmune diseases happen when the immune system makes antibodies that attack healthy tissues. Sometimes that process involves the thyroid gland and affects its ability to make hormones.
Hashimoto's disease. Hashimoto's disease is an autoimmune disorder, an illness caused by the immune system attacking healthy tissues. The damaged and inflamed tissues of the thyroid don't produce enough hormones (hypothyroidism).
The symptoms of hypothyroidism can be different from person to person. And they often look like symptoms of other health problems. Because of that, a diagnosis of hypothyroidism doesn't rely on symptoms alone. It's usually based on the results of blood tests.
Graves' disease is an immune system condition that affects the thyroid gland. It causes the body to make too much thyroid hormone. That condition is called hyperthyroidism.
Hashimoto's disease, a thyroid disorder, can cause thyroid inflammation and result in enlarged nodules. This often is associated with hypothyroidism. Multinodular goiter. The term goiter is used to describe any enlargement of the thyroid gland, which can be caused by iodine deficiency or a thyroid disorder.
In primary hyperparathyroidism, an enlargement of one or more of the parathyroid glands causes overproduction of parathyroid hormone. This causes high calcium levels in the blood, which can cause a variety of health problems. Surgery is the most common treatment for primary hyperparathyroidism.
Hyperthyroidism happens when the thyroid gland makes too much thyroid hormone. This condition also is called overactive thyroid. Hyperthyroidism speeds up the body's metabolism. That can cause many symptoms, such as weight loss, hand tremors, and rapid or irregular heartbeat.
Hashimoto thyroditis, also known as Hashimoto’s disease, is the most common cause of hypothyroidism in the U.S. “Hashimoto’s disease causes chronic inflammation of the thyroid, as antibodies form attacking your thyroid cells due to the changes to your immune mechanisms,” says Dr. Sakine Sever, a Mayo Clinic Health System endocrinologist.