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  2. Human papillomavirus infection - Wikipedia

    en.wikipedia.org/wiki/Human_papillomavirus_infection

    Human papillomavirus infection (HPV infection) is caused by a DNA virus from the Papillomaviridae family. [5] Many HPV infections cause no symptoms and 90% resolve spontaneously within two years. [1] In some cases, an HPV infection persists and results in either warts or precancerous lesions. [2] These lesions, depending on the site affected ...

  3. Pap test - Wikipedia

    en.wikipedia.org/wiki/Pap_test

    Pap test. The Papanicolaou test (abbreviated as Pap test, also known as Pap smear (AE), [1] cervical smear (BE), cervical screening (BE), [2] or smear test (BE)) is a method of cervical screening used to detect potentially precancerous and cancerous processes in the cervix (opening of the uterus or womb) or, more rarely, anus (in both men and ...

  4. Cervical intraepithelial neoplasia - Wikipedia

    en.wikipedia.org/wiki/Cervical_intraepithelial...

    The cause of CIN is chronic infection of the cervix with HPV, especially infection with high-risk HPV types 16 or 18. It is thought that the high-risk HPV infections have the ability to inactivate tumor suppressor genes such as the p53 gene and the RB gene, thus allowing the infected cells to grow unchecked and accumulate successive mutations, eventually leading to cancer.

  5. p16 - Wikipedia

    en.wikipedia.org/wiki/P16

    However, some people can have elevated levels of p16 but test negative for HPV and vice versa. This is known as discordant cancer. The 5-year survival for people who test positive for HPV and p16 is 81%, for discordant cancer it is 53–55%, and 40% for those who test negative for p16 and HPV. [33] [34]

  6. Koilocyte - Wikipedia

    en.wikipedia.org/wiki/Koilocyte

    Koilocyte. ThinPrep pap smear with group of normal cervical cells on left and HPV -infected cells showing features typical of koilocytes: enlarged (x2 or x3) nuclei and hyperchromasia. A koilocyte is a squamous epithelial cell that has undergone a number of structural changes, which occur as a result of infection of the cell by human ...

  7. Genital wart - Wikipedia

    en.wikipedia.org/wiki/Genital_wart

    Genital wart. Genital warts are a sexually transmitted infection caused by certain types of human papillomavirus (HPV). [1] They may be flat or project out from the surface of the skin, and their color may vary; brownish, white, pale yellow, pinkish-red, or gray. [1][2][3] There may be a few individual warts or several, either in a cluster or ...

  8. HPV-positive oropharyngeal cancer - Wikipedia

    en.wikipedia.org/wiki/HPV-positive_oropharyngeal...

    HPV+OPC presents in one of four ways: as an asymptomatic abnormality in the mouth found by the patient or a health professional such as a dentist; with local symptoms such as pain or infection at the site of the tumor; with difficulties of speech, swallowing, and/or breathing; or as a swelling in the neck (if the cancer has spread to lymph nodes).

  9. Papillomaviridae - Wikipedia

    en.wikipedia.org/wiki/Papillomaviridae

    Papillomaviridae is a family of non-enveloped DNA viruses whose members are known as papillomaviruses. [1] Several hundred species of papillomaviruses, traditionally referred to as "types", [2] have been identified infecting all carefully inspected mammals, [2] but also other vertebrates such as birds, snakes, turtles and fish.