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The POMC gene is located on chromosome 2p23.3. The POMC gene is expressed in both the anterior and intermediate lobes of the pituitary gland. This gene encodes a 285-amino acid polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases.
Melanocytes are melanin-producing neural crest-derived [3] cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), [4] the inner ear, [5] vaginal epithelium, [6] meninges, [7] bones, [8] and heart found in many mammals and birds. [9] Melanin is a dark pigment primarily responsible ...
They have a dominant gene that causes hyperpigmentation (Fibromelanosis), making the chicken entirely black; including feathers, beak, and internal organs. Melanism in feral rock doves are actually quite common,to some extent, especially if the area is abundant with the species. The amount of pigmentation is varied, from a slight darker ...
Hyperpigmentation can be caused by sun damage, inflammation, or other skin injuries, including those related to acne vulgaris. [1] [2] [3]: 854 People with darker skin tones are more prone to hyperpigmentation, especially with excess sun exposure. [4] Many forms of hyperpigmentation are caused by an excess production of melanin. [4]
Poikiloderma is a skin condition that consists of areas of hypopigmentation, hyperpigmentation, telangiectasias and atrophy. Poikiloderma of Civatte is most frequently seen on the chest or the neck, characterized by red colored pigment on the skin that is commonly associated with sun damage. [1]
[6] [7] [8] Quizlet's blog, written mostly by Andrew in the earlier days of the company, claims it had reached 50,000 registered users in 252 days online. [9] In the following two years, Quizlet reached its 1,000,000th registered user. [10] Until 2011, Quizlet shared staff and financial resources with the Collectors Weekly website. [11]
[citation needed] Nonetheless, chemical databases such as PubChem include structural and empirical formulae; typically 3,8-Dimethyl-2,7-dihydrobenzo[1,2,3-cd:4,5,6-c′d′]diindole-4,5,9,10-tetrone. This can be thought of as a single monomer that accounts for the measured elemental composition and some properties of melanin, but is unlikely to ...
Melasma (also known as chloasma faciei, [1]: 854 or the mask of pregnancy [2] when present in pregnant women) is a tan or dark skin discoloration.Melasma is thought to be caused by sun exposure, genetic predisposition, hormone changes, and skin irritation. [3]