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Fexofenadine, sold under the brand name Allegra among others, [10] is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria. [11] Therapeutically, fexofenadine is a selective peripheral H 1 blocker.
H 1 antagonists, also called H 1 blockers, are a class of medications that block the action of histamine at the H 1 receptor, helping to relieve allergic reactions. Agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines ; other agents may have antihistaminergic action but are ...
The Schedule 2 list is one of three lists. Chemicals that can be used as weapons, or used in their manufacture, but that have no, or almost no, legitimate applications as well are listed in Schedule 1, whilst Schedule 3 is used for chemicals that also have widespread industrial uses. The use of Schedule 1, 2, or 3 chemicals as weapons is banned ...
H 1-antihistamines work by binding to histamine H 1 receptors in mast cells, smooth muscle, and endothelium in the body as well as in the tuberomammillary nucleus in the brain. Antihistamines that target the histamine H 1 -receptor are used to treat allergic reactions in the nose (e.g., itching, runny nose, and sneezing).
The following findings are required, by section 202 of that Act, for substances to be placed in this schedule: The drug or other substance has a high potential for abuse. The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions.
[1] [2] Histamine receptors are proteins that bind with histamine, a neurotransmitter involved in various physiological processes. There are four main types: H1, H2, H3, and H4. H1 receptors are linked to allergic responses, H2 to gastric acid regulation, H3 to neurotransmitter release modulation, and H4 to immune system function.
This is the list of Schedule I controlled substances in the United States as defined by the Controlled Substances Act. [1] The following findings are required for substances to be placed in this schedule: [2]
Schedules 2 and 3 chemicals produced on their territory must also be reported in the annual statement insofar as the quantity thereof has exceeded a certain threshold value. [8] With a few exceptions, only annually produced quantities above 100 kg of List 2 substances from Part A or 1000 kg of a precursor from Part B must be reported to the ...