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Canesten brand Clotrimazole antifungal cream Clotrimazole is available as a generic medication , [2] and in 2016 Canesten brand Clotrimazole was one of the biggest-selling branded over-the-counter medications sold in Great Britain, with sales of £39.2 million.
Aqueous Cream BP, also known as sorbolene, is a light, hydrocarbon-based emulsion, which is officially registered in the British Pharmacopoeia and categorised by the British National Formulary as a non-proprietary emollient preparation. [1]
Alkylation of imidazole (2) with bromoketone (1) prepared from o,p-dichloroacetophenone affords the displacement product (3). Reduction of the ketone with sodium borohydride gives the corresponding alcohol ( 4 ).
Topically administered ketoconazole is usually prescribed for fungal infections of the skin and mucous membranes, such as athlete's foot, ringworm, candidiasis (yeast infection or thrush), jock itch, and tinea versicolor. [20]
An antiseptic (Greek: ἀντί, romanized: anti, lit. 'against' [1] and σηπτικός, sēptikos, 'putrefactive' [2]) is an antimicrobial substance or compound that is applied to living tissue to reduce the possibility of sepsis, infection, or putrefaction.
[3] [1] [6] [10] Gel characteristics include stability, thermodynamic activity, and occlusive properties. [3] [1] [10] Following penetration through the skin barrier, the drug may permeate through deeper skin tissues and reach the blood capillaries in the dermis. [6] [9] It may then proceed to enter the systemic circulation for systemic effect ...
Ozenoxacin, sold under the brand names Ozanex and Xepi, is a quinolone antibiotic used for the treatment of impetigo. [4] A 1% topical cream is approved for treatment of impetigo in Canada [5] and in the United States.
2-Methylimidazole (1) may be prepared via the Debus-Radziszewski imidazole synthesis, or from ethylenediamine and acetic acid, followed by treatment with lime, then Raney nickel. 2-Methylimidazole is nitrated to give 2-methyl-4(5)-nitroimidazole (2), which is in turn alkylated with ethylene oxide or 2-chloroethanol to give metronidazole (3 ...
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