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The serial comma (for example the comma before and in "ham, chips, and eggs") is optional; be sensitive to possible ambiguity arising from thoughtless use or thoughtless avoidance, and be consistent within a given article. Avoid comma splices. Picture captions should not end in a full stop (a period) unless they are complete sentences.
Some people use the Oxford comma (also known as the Harvard or serial comma). This is a comma before "and" or "or" at the end of a series, regardless of whether it is needed for clarification purposes. For example: X, Y, and Z (with an Oxford comma) X, Y and Z (without an Oxford comma)
This sentence is a bit different; however, a comma is necessary as well. Using commas to offset certain adverbs is optional, including then, so, yet, instead, and too (meaning also). So, that's it for this rule. or; So that's it for this rule. A comma would be appropriate in this sentence, too. or; A comma would be appropriate in this sentence too.
The comma-free approach is often used with partial quotations: The report observed "a 45% reduction in transmission rate". A comma is required when it would be present in the same construction if none of the material were a quotation: In Margaret Mead's view, "we must recognize the whole gamut of human potentialities" to enrich our culture.
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"A comma is used before and, or, or etc. in a list when its omission might either give rise to ambiguity or cause the last word or phrase to be construed with a preposition in the preceding phrase. … Generally, however, a comma is not used before and, or or etc. in a list."
Wikipedia's Manual of Style contains some conventions that differ from those in some other, well-known style guides and from what is often taught in schools.Wikipedia's editors have discussed these conventions in great detail and have reached consensus that these conventions serve our purposes best.