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  2. Pembrolizumab - Wikipedia

    en.wikipedia.org/wiki/Pembrolizumab

    Pembrolizumab, sold under the brand name Keytruda, is a humanized antibody, more specifically a PD-1 inhibitor, used in cancer immunotherapy that treats melanoma, lung cancer, head and neck cancer, Hodgkin lymphoma, stomach cancer, cervical cancer, and certain types of breast cancer. [12] [14] [15] [16] It is administered by slow intravenous ...

  3. PD-1 and PD-L1 inhibitors - Wikipedia

    en.wikipedia.org/wiki/PD-1_and_PD-L1_inhibitors

    Pembrolizumab (Keytruda, formerly MK-3475 and lambrolizumab) was developed by Merck and first approved by the Food and Drug Administration in 2014 for the treatment of melanoma. It was later approved for metastatic non-small cell lung cancer and head and neck squamous cell carcinoma. In 2017, it became the first immunotherapy drug approved for ...

  4. Checkpoint inhibitor - Wikipedia

    en.wikipedia.org/wiki/Checkpoint_inhibitor

    It was approved in 2014. Nivolumab is approved to treat melanoma, lung cancer, kidney cancer, bladder cancer, head and neck cancer, and Hodgkin's lymphoma. [16] Pembrolizumab (brand name Keytruda) is another PD-1 inhibitor that was approved by the FDA in 2014 and was the second checkpoint inhibitor approved in the United States. [17]

  5. Merck Nabs Expanded Keytruda Label For Hodgkin Lymphoma - AOL

    www.aol.com/news/merck-nabs-expanded-keytruda...

    Merck (MRK) has announced that the U.S. Food and Drug Administration (FDA) has approved an expanded label for Keytruda, Merck’s anti-PD-1 therapy, as monotherapy for the treatment of adult ...

  6. Merck's Keytruda combo gets FDA nod for expanded use in ... - AOL

    www.aol.com/news/mercks-keytruda-combo-gets-fda...

    Keytruda is already approved as a combination therapy and a monotherapy to treat patients with two other types of cervical cancers. The drug, which is set to lose certain U.S. patents toward the ...

  7. Merck's Keytruda gets FDA nod for expanded use in lung cancer

    www.aol.com/news/mercks-keytruda-gets-u-fdas...

    The U.S. health regulator's approval extends Keytruda's use in combination with chemotherapy as a treatment given before surgery to shrink the size of the tumor in patients. The U.S. drugmaker is ...

  8. Merck's Keytruda Gets FDA Nod for 2nd Lymphoma Indication - AOL

    www.aol.com/news/merck-apos-keytruda-gets-fda...

    Merck's (MRK) Keytruda gets FDA approval for primary mediastinal B-cell lymphoma (PMBCL) - its second label expansion approval this week.

  9. List of largest selling pharmaceutical products - Wikipedia

    en.wikipedia.org/wiki/List_of_largest_selling...

    Main indication Trade name 2018 sales (million USD) 2017 sales (million USD) 1 adalimumab: rheumatoid arthritis: Humira 19 936 18427 3 apixaban: anticoagulant: Eliquis 9872 7395 4 lenalidomide: multiple myeloma: Revlimid 9685 8187 5 nivolumab: oncology: Opdivo 7570 5763 6 pembrolizumab: oncology: Keytruda 7171 3809 7 etanercept: rheumatoid ...

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