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One such cause is chemical imbalances in the brain, which can lead to irrational decisions and emotional pain. [8] For example, when the brain lacks serotonin, a chemical that regulates the brain's functioning, it can lead to depression, appetite changes, aggression, and anxiety. Another cause of mental distress can be exposure to severely ...
Many psychologists criticise psychiatry for focusing its attention primarily on symptoms and for assuming that relieving symptoms with drugs cures the problem. Unfortunately, in many cases when the drug treatment is ceased the symptoms recur. This suggests that drugs are not addressing the true cause of the problem. [4]
The pharmacology of antidepressants is not entirely clear.. The earliest and probably most widely accepted scientific theory of antidepressant action is the monoamine hypothesis (which can be traced back to the 1950s), which states that depression is due to an imbalance (most often a deficiency) of the monoamine neurotransmitters (namely serotonin, norepinephrine and dopamine). [1]
There are several main groups. Antidepressants are used for the treatment of clinical depression as well as often for anxiety and other disorders. [30] Anxiolytics are used, generally short-term, for anxiety disorders and related problems such as physical symptoms and insomnia. [31]
Biological psychiatry or biopsychiatry is an approach to psychiatry that aims to understand mental disorder in terms of the biological function of the nervous system.It is interdisciplinary in its approach and draws on sciences such as neuroscience, psychopharmacology, biochemistry, genetics, epigenetics and physiology to investigate the biological bases of behavior and psychopathology.
On the other hand, other medications that increase dopamine levels have also been found to improve anxiety. [42] Many physical symptoms of anxiety, such as rapid heart rate and hand tremors, are regulated by norepinephrine. Drugs that counteract norepinephrine's effect may be effective in reducing the physical symptoms of a panic attack. [42]
The serotonin "chemical imbalance" theory of depression, proposed in the 1960s, [35] is not supported by the available scientific evidence. [ 35 ] [ 36 ] SSRIs alter the balance of serotonin inside and outside of neurons: their clinical antidepressant effect (which is robust in severe depression [ 37 ] ) is likely due to more complex changes in ...
A prolonged depressed mood, especially in combination with other symptoms, may lead to a diagnosis of a psychiatric or medical condition which may benefit from treatment. The UK National Institute for Health and Care Excellence (NICE) 2009 guidelines indicate that antidepressants should not be routinely used for the initial treatment of mild ...
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