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Structural model at atomic resolution of bacteriophage T4 [1] The structure of a typical myovirus bacteriophage Anatomy and infection cycle of bacteriophage T4.. A bacteriophage (/ b æ k ˈ t ɪər i oʊ f eɪ dʒ /), also known informally as a phage (/ ˈ f eɪ dʒ /), is a virus that infects and replicates within bacteria and archaea.
[56] [57] Viruses, just like bacteria, can evolve resistance to different treatments. [58] Bacteriophages are very specific, targeting only one or a few strains of bacteria. [59] Traditional antibiotics have a more wide-ranging effect, killing both harmful and useful bacteria, such as those facilitating food digestion. [60]
The interaction of phage with bacteria is the primary concern of phage community ecologists. Bacteria have developed mechanisms that prevent phages from having an effect on them, which has led to this evolutionary arms race between the phages and their host bacteria. [14]
The dominant hosts for viruses in the ocean are marine microorganisms, such as bacteria. [14] Bacteriophages are harmless to plants and animals, and are essential to the regulation of marine and freshwater ecosystems [91] are important mortality agents of phytoplankton, the base of the foodchain in aquatic environments. [92]
Bacteria also live in symbiotic and parasitic relationships with plants and animals. Once regarded as plants constituting the class Schizomycetes , bacteria are now classified as prokaryotes . Unlike cells of animals and other eukaryotes , bacterial cells do not contain a nucleus and rarely harbour membrane-bound organelles .
Once the T7 phage has inserted the viral genome, the process of DNA replication of the host genome is halted and replication of viral genome begins. [19] Under optimal conditions, the T7 phage can complete the lytic process within 25 minutes, leading to the death of the E. coli host cell. At the time of lysis, the virus can produce over 100 ...
Metagenomic sequence-based analyses have been used to predict around 57 complete and partial virophage genomes [9] and in December 2019 to identify 328 high-quality (complete or near-complete) genomes from diverse habitats including the human gut, plant rhizosphere, and terrestrial subsurface, from 27 distinct taxonomic clades.
A prophage is a bacteriophage (often shortened to "phage") genome that is integrated into the circular bacterial chromosome or exists as an extrachromosomal plasmid within the bacterial cell. [1] Integration of prophages into the bacterial host is the characteristic step of the lysogenic cycle of temperate phages.