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Mirtazapine, sold under the brand name Remeron among others, is an atypical tetracyclic antidepressant, and as such is used primarily to treat depression. [11] [12] Its effects may take up to four weeks but can also manifest as early as one to two weeks. [12] [13] It is often used in cases of depression complicated by anxiety or insomnia.
[8] [1] Unlike low-dose mirtazapine, the half life (10 hours) is short enough that next-day sedation may be manageable, however, for people with CYP2D6 polymorphisms, which constitute a sizable fraction of the population, the half-life is expected to be quite a bit longer. Merck researchers claimed that the incidence of next-day sedation was ...
In addition, due to their blockade of certain serotonin receptors, serotonergic neurotransmission is not facilitated in unwanted areas, which prevents the incidence of many side effects often associated with selective serotonin reuptake inhibitor (SSRI) antidepressants; [1] [3] hence, in part, the "specific serotonergic" label of NaSSAs. [2]
Past clinical studies have shown users of the medications can lose between 5% and 20% of their body weight on the medications over time. The most commonly reported side effects of medications used ...
Menopause is a nearly universal experience for women who live to middle age. In the United States, an estimated 1.3 million women enter menopause every year. Around 90% of women experience ...
In response to Winfrey’s story, Shriver pointed out how important it is to be vigilant about menopausal diagnoses. “Most people at Oprah’s age, when they would go [to the doctor], a lot of ...
A number of non-SSRI drugs are not associated with sexual side effects (such as bupropion, mirtazapine, tianeptine, agomelatine, tranylcypromine, and moclobemide [56] [57] [58]). Several studies have suggested that SSRIs may adversely affect semen quality. [59] [60]
As women begin to hit perimenopause and menopause, some start to question their identity, struggle with big life stressors like caring for aging parents, divorce, age discrimination at work, and ...