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Drug-induced lupus erythematosus is an autoimmune disorder caused by chronic use of certain drugs.These drugs cause an autoimmune response (the body attacks its own cells) producing symptoms similar to those of systemic lupus erythematosus (SLE).
Drug-induced lupus erythematosus is a (generally) reversible condition that usually occurs in people being treated for a long-term illness. Drug-induced lupus mimics SLE. However, symptoms of drug-induced lupus generally disappear once the medication that triggered the episode is stopped.
Patients with drug-induced lupus erythematosus typically have positive tests for anti-histone antibodies but do not have indications for anti-dsDNA antibodies. Patients with idiopathic systemic lupus erythematosus have both types of autoantibodies present in their blood. Thus, this test can be useful in distinguishing these two illnesses. [9]
The oral drug, brepocitinib, did not meet the primary study goal of reduction in disease activity at week 52 in patients of SLE, in which the immune system that normally helps protect the body ...
Common symptoms include extreme fatigue, joint pain or skin rashes. In rare cases, the disease may lead to kidney or heart damage, or weaken the immune system so the body can’t fight off infections.
“In SLE patients taking significant immunosuppressive medications, live vaccines are usually avoided due to the risk of excessive viral replication, leading to severe and life-threatening ...
cSLE, Juvenile-onset systemic lupus erythematosus, juvenile systemic lupus erythematosus, and pediatric systemic lupus erythematosus: Specialty: Rheumatology: Usual onset: Children up to 17 years old: Types: Early-onset SLE is a type of cSLE that occurs in children up to 5 years old. It tends to be more severe than cSLE in older children. Causes
Scientists at Northwestern Medicine may have discovered the cause of lupus. Here's what to know about the breakthrough and what it means for lupus treatments. The Root Cause Of Lupus Has Been A ...
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