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Lidocaine is an antiarrhythmic medication of the class Ib type. [8] This means it works by blocking sodium channels thus decreasing the rate of contractions of the heart. [11] [8] When injected near nerves, the nerves cannot conduct signals to or from the brain. [9] Lidocaine was discovered in 1946 and went on sale in 1948. [12]
Local anesthetic injections are given in specific areas of the mouth, rather than the whole body. Although several different medications are available, the most commonly used local anesthetic to prevent pain in the area around a tooth is lidocaine (also called xylocaine or lignocaine). Lidocaine's half-life in the body is about 1.5–2 hours. [2]
[7] Most commonly, hyperosmolar dextrose (a sugar) is the solution used; [23] glycerine, [20] lidocaine (a commonly used local anesthetic), [24] phenol, [20] and sodium morrhuate (a derivative of cod liver oil extract) are other commonly used agents. [7] [9] The injection is administered at joints, ligaments, or tendons where they connect to bone.
Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes ...
Artecoll is a gel suspension of 20% polymethylmethacrylate (PMMA) 30- to 42-micron microspheres, 3.5% collagen derived from cows, and 0.3% lidocaine. [1] [2] The PMMA microspheres in Artecoll are not absorbed by the body and therefore provide a permanent scaffold into which the person's own soft tissue can grow; the PMMA microspheres can only be removed by cutting them out.
Overall, the procedure involves injecting a local anesthetic drug (e.g. lidocaine or bupivicaine) with a 20 gauge spinal needle near the pudendal nerve in order to provide pain relief. [1] [2] Lidocaine is usually preferred for a pudendal block because it has a longer duration than chloroprocaine which usually lasts less than one hour. [5]
Single-injection techniques provide unreliable blockade in the areas supplied by the musculocutaneous and radial nerves. Current evidence suggests that a triple-stimulation technique — with injections on the musculocutaneous, median and radial nerves — is the best technique for the axillary block. [11]
Aside from its use as a dental anesthetic, procaine is used less frequently today, since more effective (and hypoallergenic) alternatives such as lidocaine (Xylocaine) exist. Like other local anesthetics (such as mepivacaine , and prilocaine ), procaine is a vasodilator, thus is often coadministered with epinephrine for the purpose of ...
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