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Treatment is typically by observation or surgical removal. [1] Rarely, the condition may recur following removal, but this can generally be managed with repeat surgery. [1] They are not generally associated with a future risk of cancer. [1] Lipomas have a prevalence of roughly 2 out of every 100 people. [2]
The only effective treatments for lipomas caused by familial multiple lipomatosis are liposuction or surgical removal. [6] Steroid injections may also be used to shrink the tumors by causing local fat atrophy. [7] Patients with the condition often seek removal when the lipomas are large, disfiguring, or cause pain. [2]
Removal can include simple excision, endoscopic removal, or liposuction. [ 1 ] Other entities which are accompanied by multiple lipomas include Proteus syndrome , Cowden syndrome and related disorders due to PTEN gene mutations, benign symmetric lipomatosis ( Madelung disease ), Dercum's Disease, familial lipodystrophy , hibernomas , epidural ...
For example, a lipoma is a common benign tumor of fat cells , and a chondroma is a benign tumor of cartilage-forming cells (chondrocytes). Adenomas are benign tumors of gland-forming cells, and are usually specified further by their cell or organ of origin, as in hepatic adenoma (a benign tumor of hepatocytes , or liver cells).
Benign symmetric lipomatosis, also known as Madelung's disease, is an adult-onset skin condition characterized by extensive symmetric fat deposits in the head, neck, and shoulder girdle area. [1]
Liposuction, or simply lipo, is a type of fat-removal procedure used in plastic surgery. [1] Evidence does not support an effect on weight beyond a couple of months and does not appear to affect obesity-related problems. [2] [3] In the United States, liposuction is the most common cosmetic surgery. [4] [5]
The post-surgical risk of recurrence within 3 years after surgery has been reported to be ~15% when not all tumor is removed and ~10% when tumor removal is complete. [40] The addition of radiotherapy to surgical resection has improved the local control of MLS tumors and has been recommended to treat unresectable and recurrent MLS. [45]
Surgery often requires general anesthesia and a day in the hospital, and can leave significant scarring at the site of the incision. Minimally-invasive surgical alternatives include biopsy-removal techniques and cryoablation. Biopsy-removal involves using a vacuum-assisted biopsy device to remove the fibroadenoma bit by bit.
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