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Chiral drugs. Chemical compounds that come as mirror-image pairs are referred to by chemists as chiral or handed molecules. [ 1 ] Each twin is called an enantiomer. Drugs that exhibit handedness are referred to as chiral drugs. Chiral drugs that are equimolar (1:1) mixture of enantiomers are called racemic drugs and these are obviously devoid ...
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs ...
David A. Evans (January 11, 1941 – April 29, 2022) [1] [2] [3] was an American chemist who was the Abbott and James Lawrence professor of chemistry at Harvard University. [4] [5] He was a prominent figure in the field of organic chemistry and his research focused on synthetic chemistry and total synthesis, particularly of large biologically active molecules.
Organoboron chemistry or organoborane chemistry studies organoboron compounds, also called organoboranes. These chemical compounds combine boron and carbon; typically, they are organic derivatives of borane (BH 3), as in the trialkyl boranes. [1][2] Organoboranes and -borates enable many chemical transformations in organic chemistry — most ...
D010600. Pharmacology is the science of drugs and medications, [1] including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. [2]
Click chemistry is an approach to chemical synthesis that emphasizes efficiency, simplicity, selectivity, and modularity in chemical processes used to join molecular building blocks. It includes both the development and use of "click reactions", a set of simple, biocompatible chemical reactions that meet specific criteria like high yield, fast ...
Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs). The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for example, infection). Pharmacodynamics and pharmacokinetics are the main branches of pharmacology ...
Pharmaceutics is the discipline of pharmacy that deals with the process of turning a new chemical entity (NCE) or old drugs into a medication to be used safely and effectively by patients. Pharmaceutics helps relate the formulation of drugs to their delivery and disposition in the body. [1] Pharmaceutics deals with the formulation of a pure ...