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2. Adapalene/benzoyl peroxide - Wikipedia

   en.wikipedia.org/wiki/Adapalene/benzoyl_peroxide

   Meta-analysis of clinical trials has shown this combined therapy to be more effective than either of its ingredients by themselves. [6]The use of adapalene/benzoyl peroxide in combination with oral antibiotics (lymecycline) has been studied; [7] the combination was well tolerated and showed an improved success rate compared to those receiving only antibiotics (47.6% vs. 33.7%, P = 0.002).

3. Adapalene - Wikipedia

   en.wikipedia.org/wiki/Adapalene

   Adapalene Gel, sold in trade name Differin in China Adapalene , sold under the brand name Differin among others, is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne , and is also used off-label to treat keratosis pilaris as well as other skin conditions. [ 6 ]

4. Pennsylvania - Wikipedia

   en.wikipedia.org/wiki/Pennsylvania

   Pennsylvania (/ ˌ p ɛ n s ɪ l ˈ v eɪ n i ə / ⓘ PEN-sil-VAY-nee-ə, lit. ' Penn's forest country '), officially the Commonwealth of Pennsylvania [b] (Pennsylvania Dutch: Pennsilfaani), [7] is a U.S. state spanning the Mid-Atlantic, Northeastern, Appalachian, and Great Lakes regions of the United States.