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Diagramatic representation of mucosal erosion (left), excoriation (center), and ulceration (right) Simplistic representation of the life cycle of mouth ulcers. An ulcer (/ ˈ ʌ l s ər /; from Latin ulcus, "ulcer, sore") [2] is a break in the skin or mucous membrane with loss of surface tissue and the disintegration and necrosis of epithelial tissue. [3]
Behçet's disease is a triad of mouth ulcers, genital ulcers and anterior uveitis. [8] The main feature of Behçet's disease is aphthous-like ulceration, but this is usually more severe than seen in aphthous stomatitis without a systemic cause, and typically resembles major or herpetiforme ulceration or both.
The individual ulcers (aphthae) recur periodically and heal completely, although in the more severe forms, new ulcers may appear in other parts of the mouth before the old ones have finished healing. Aphthous stomatitis is one of the most common diseases of the oral mucosa , and is thought to affect about 20% of the general population to some ...
Symptomatic relief of the pain of oral mucositis may be provided by barrier protection agents such as concentrated oral gel products (e.g. Gelclair). Caphosol is a mouth rinse which has been shown to prevent and treat oral mucositis caused by radiation and high-dose chemotherapy.
Anti-ulcer agents are medications or supplements used to cure the damage of mucosal layer on organs to prevent the damage from further extending to deeper regions to cause complications. An anti-ulcer medication for treating mouth ulcer is triamcinolone, a corticosteroid. Other anti-ulcer supplements include vitamin B2 and vitamin B12.
Signs include skin hyperpigmentation, alabaster-coloured pale skin, low blood pressure, postural hypotension. Skin pigmentation have increased deposition in the palmer skin creases, nails and gingiva. [13] Management of Addison's is with steroids. During dental treatment the patient may require an increased dose of steroids based on treatment need.
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Mouth and genital ulcers with inflamed cartilage syndrome or MAGIC syndrome is a condition in which an individual exhibits symptoms of both relapsing polychondritis (RP) and Behcet's disease (BD). [1] Inflammatory ulcers in the mouth, genitalia, and skin are the hallmark of Behcet's disease (BD), a multisystem illness that is chronic and ...