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The first medical use of fumaric acid was described in 1959 by Walter Schweckendiek, a German chemist, [15] and was a topical formulation for psoriasis. The Swiss company Fumapharm eventually brought Fumaderm, an oral formulation of dimethyl fumarate (along with some monoesters) to market for psoriasis in Germany in 1994. [16] [17] [18]
Fumaric acid was developed as a medicine to treat the autoimmune condition psoriasis in the 1950s in Germany as a tablet containing 3 esters, primarily dimethyl fumarate, and marketed as Fumaderm by Biogen Idec in Europe. Biogen would later go on to develop the main ester, dimethyl fumarate, as a treatment for multiple sclerosis.
In May 2006, the company announced it would acquire cancer specialist, Conforma Therapeutics for $250 million. [12] Later in the same month, the company announced its intention to acquire Fumapharm AG, consolidating ownership of Fumaderm and BG-12, an oral fumarate, which was being studied for the treatment of multiple sclerosis and psoriasis. [13]
The company was founded in 1992. In 1999, MorphoSys listed on the Frankfurt Stock Exchange under the ticker symbol "MOR". In 2004, MorphoSys and Novartis entered into a strategic partnership for the research and development of biopharmaceuticals, which was expanded in 2007. [1]
3. Avoid High-Fat Foods and Other Triggers. High-fat foods can make your nausea worse. Try avoiding: Fatty meats. Baked goods. Greasy or fried foods
Christina Haack has someone new in her life!. The Christina on the Coast star, 41, is dating a new man following her split from estranged husband Josh Hall last summer, PEOPLE has confirmed. The ...
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