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  2. Tiagabine - Wikipedia

    en.wikipedia.org/wiki/Tiagabine

    Tiagabine is primarily used as an anticonvulsant in the treatment of epilepsy as a supplement. Although the exact mechanism by which Tiagabine exerts its antiseizure effect is unknown, it is thought to be related to its ability to increase the activity of gamma aminobutyric acid (GABA), the central nervous system's major inhibitory ...

  3. Muscimol - Wikipedia

    en.wikipedia.org/wiki/Muscimol

    Muscimol is a potent GABA A agonist, activating the receptor for the brain's principal inhibitory neurotransmitter, GABA. Muscimol binds to the same site on the GABA A receptor complex as GABA itself, as opposed to other GABAergic drugs such as barbiturates and benzodiazepines which bind to separate regulatory sites. [ 10 ]

  4. GABA tea - Wikipedia

    en.wikipedia.org/wiki/GABA_Tea

    GABA oolong teas from Taiwan are also another common type of GABA tea. Traditionally it was thought that exogenous GABA did not penetrate [ 8 ] the blood–brain barrier , however more current research indicates that it may be possible, or that exogenous GABA (i.e. in the form of nutritional supplements) could exert GABAergic effects on the ...

  5. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    Gabapentin is recommended for use in focal seizures and neuropathic pain. [7] [10] Gabapentin is prescribed off-label in the US and the UK, [22] [23] for example, for the treatment of non-neuropathic pain, [22] anxiety disorders, sleep problems and bipolar disorder. [24]

  6. Valerenic acid - Wikipedia

    en.wikipedia.org/wiki/Valerenic_acid

    A small study with six human subjects found that valerenic acid peaked in concentration after about an hour and had an average half-life of 1.1 +/- 0.6 hours after oral ingestion of a commercially available valerian root supplement. [8] A later study from the same lab done with sixteen older women found similar values. [3]

  7. Picamilon - Wikipedia

    en.wikipedia.org/wiki/Picamilon

    Picamilon (also known as N-nicotinoyl-GABA, pycamilon, and pikamilon) is a drug formed by a synthetic combination of niacin and γ-aminobutyric acid (GABA). It was developed in the Soviet Union in 1969 [3] and further studied in both Russia [4] and Japan as a prodrug of GABA. [5] In Russia, picamilon is sold as a prescription drug.

  8. GABA reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/GABA_reuptake_inhibitor

    A GABA reuptake inhibitor (GRI) is a type of drug which acts as a reuptake inhibitor for the neurotransmitter gamma-Aminobutyric acid (GABA) by blocking the action of the gamma-Aminobutyric acid transporters (GATs). This in turn leads to increased extracellular concentrations of GABA and therefore an increase in GABAergic neurotransmission. [1]

  9. Gabapentinoid - Wikipedia

    en.wikipedia.org/wiki/Gabapentinoid

    The gabapentinoids are 3-substituted derivatives of GABA; hence, they are GABA analogues, as well as γ-amino acids. [3] [4] Specifically, pregabalin is (S)-(+)-3-isobutyl-GABA, phenibut is 3-phenyl-GABA, [28] and gabapentin is a derivative of GABA with a cyclohexane ring at the 3 position (or, somewhat inappropriately named, 3-cyclohexyl-GABA).