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There is a strong advocacy movement for very high doses of vitamin C, yet there is an absence of large-scale, formal trials in the 10 to 200+ grams per day range. The single repeatable side effect of oral megadose vitamin C is a mild laxative effect if the practitioner attempts to
Beginning in the 1930s in Canada, a megadose vitamin E therapy for cardiovascular and circulatory complaints was developed by Evan Shute and colleagues, named the "Shute protocol". [15] Tentative experiments in the 1930s by Claus W. Jungeblut [ 16 ] with larger doses of vitamin C led to Frederick Klenner's development of megadose intravenous ...
Vitamin C and the Common Cold is a popular book by Linus Pauling, first published in 1970, on vitamin C, its interactions with common cold and the role of vitamin C megadosage in human health. [1] The book promoted the idea that taking large amounts of vitamin C could reduce the duration and severity of the common cold .
The Benefits of Vitamin C. ... often about 100 mg per supplement, so an additional high dose vitamin C supplement is not necessary,” says Braslow. London agrees, adding that unless a physician ...
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[10] [11] A systematic review of trials in 2021 found that the claimed benefits of the protocol could not be confirmed. [12] People in sepsis may have micronutrient deficiencies, including low levels of vitamin C. [13] Reviews mention that an intake of 3.0 g/day via intravenous administration may needed to maintain normal plasma concentrations.
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