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Shigella is a genus of bacteria that is Gram negative, facultatively anaerobic, non–spore-forming, nonmotile, rod shaped, and is genetically nested within Escherichia. The genus is named after Kiyoshi Shiga, who discovered it in 1897. [1] Shigella causes disease in primates, but not in other mammals; it is the causative agent of human ...
Shigellosis, known historically as dysentery, is an infection of the intestines caused by Shigella bacteria. [1] [3] Symptoms generally start one to two days after exposure and include diarrhea, fever, abdominal pain, and feeling the need to pass stools even when the bowels are empty. [1]
Shigella dysenteriae is a species of the rod-shaped bacterial genus Shigella. [1] Shigella species can cause shigellosis (bacillary dysentery). Shigellae are Gram-negative, non-spore-forming, facultatively anaerobic, nonmotile bacteria. [2] S. dysenteriae has the ability to invade and replicate in various species of epithelial cells and ...
For example, Shigella is a longstanding World Health Organization (WHO) target for vaccine development, and sharp declines in age-specific diarrhea/dysentery attack rates for this pathogen indicate that natural immunity does develop following exposure; thus, vaccination to prevent this disease should be feasible. The development of vaccines ...
Shigella sonnei is a species of Shigella. [2] Together with Shigella flexneri, it is responsible for 90% of shigellosis cases. [3] Shigella sonnei is named for the Danish bacteriologist Carl Olaf Sonne. [4] [5] It is a Gram-negative, rod-shaped, nonmotile, non-spore-forming bacterium. [6]
Shigella flexneri is a rod shaped, nonflagellar bacterium that relies on actin-based motility. It produces the protein actin in a swift and continuous fashion to propel itself forward within and between the host's cells. [4] This bacterium is gram-negative, non-spore forming Shigella from serogroup B. There are 6 serotypes within this serogroup.
The term is usually restricted to Shigella infections. [2] Shigellosis is caused by one of several types of Shigella bacteria. [3] Three species are associated with bacillary dysentery: Shigella sonnei, Shigella flexneri and Shigella dysenteriae. [4] A study in China indicated that Shigella flexneri 2a was the most common serotype. [5]
Shigella boydii is a Gram-negative bacterium of the genus Shigella. Like other members of the genus, S. boydii is a nonmotile, nonsporeforming, rod-shaped bacterium which can cause dysentery in humans through fecal-oral contamination. [1] [page needed] Shigella boydii is the most genetically divergent species of the genus Shigella. [2]