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Thrombotic thrombocytopenic purpura (TTP) is a blood disorder that results in blood clots forming in small blood vessels throughout the body. [2] This results in a low platelet count , low red blood cells due to their breakdown , and often kidney , heart , and brain dysfunction. [ 1 ]
Pentad of TTP: Remembered by the mnemonic "FAT RN" (or alternatively "ART FaN"); Fever, Anemia (microangiopathic hemolytic anemia), Thrombocytopenia, Renal failure, Neurologic disturbances: Thrombotic thrombocytopenic purpura: Pentalogy of Cantrell: Omphalocele, Anterior diaphragmatic hernia, Sternal cleft, Ectopia cordis, Intracardiac defect.
Treatment of thrombotic thrombocytopenic purpura (TTP) is a medical emergency, since the associated hemolytic anemia and platelet activation can lead to kidney failure and changes in the level of consciousness. Treatment of TTP was revolutionized in the 1980s with the application of plasmapheresis.
Another form is thrombotic thrombocytopenic purpura. [citation needed] Diagnosis
The study found that 15.3% of participants had mild cognitive impairment, and that women with mild cognitive impairment were more likely to report more severe menopause symptoms.
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