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  2. Hepatotoxin - Wikipedia

    en.wikipedia.org/wiki/Hepatotoxin

    A hepatotoxin (Gr., hepato = liver) is a toxic chemical substance that damages the liver. It can be a side-effect , but hepatotoxins are also found naturally, such as microcystins and pyrrolizidine alkaloids , or in laboratory environments, such as carbon tetrachloride , or far more pervasively in the form of ethanol (drinking alcohol).

  3. Category:Hepatotoxins - Wikipedia

    en.wikipedia.org/wiki/Category:Hepatotoxins

    Drugs and other substances that have been associated with significant hepatotoxicity (liver damage). Subcategories ...

  4. Hepatotoxicity - Wikipedia

    en.wikipedia.org/wiki/Hepatotoxicity

    Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval.

  5. List of withdrawn drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_withdrawn_drugs

    Hepatotoxicity. [3] Fenfluramine: 1997 European Union, UK, US, India, South Africa, others Cardiac valvular disease, pulmonary hypertension, cardiac fibrosis; [3] [23] re-approved in June 2020 for the treatment of seizures associated with Dravet syndrome, under FDA orphan drug rules. Fenoterol: 1990 New Zealand Asthma mortality. [3] Feprazone ...

  6. Tetracycline antibiotics - Wikipedia

    en.wikipedia.org/wiki/Tetracycline_antibiotics

    Prescriptions of these drugs should be discarded once expired because they can cause hepatotoxicity. It was once believed that tetracycline antibiotics impair the effectiveness of many types of hormonal contraception. Recent research has shown no significant loss of effectiveness in oral contraceptives while using most tetracyclines.

  7. Hepatitis - Wikipedia

    en.wikipedia.org/wiki/Hepatitis

    Fulminant hepatitis, or massive hepatic cell death, is a rare and life-threatening complication of acute hepatitis that can occur in cases of hepatitis B, D, and E, in addition to drug-induced and autoimmune hepatitis.

  8. Rifampicin - Wikipedia

    en.wikipedia.org/wiki/Rifampicin

    Rifampicin is the most powerful known inducer of the hepatic cytochrome P450 enzyme system, including isoenzymes CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP3A4, CYP3A5, and CYP3A7. [42] It increases metabolism of many drugs [43] and as a consequence, can make them less effective, or even ineffective, by decreasing their levels. [44]

  9. List of antineoplastic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_antineoplastic_agents

    Malignant melanoma of the extremities, multiple myeloma, conditioning treatment before haemopoietic stem cell transplant. Myelosuppression, pulmonary fibrosis and pneumonitis (uncommon), skin necrosis (uncommon), anaphylaxis, hepatic sinusoidal obstruction syndrome and SIADH. Secondary malignancies. [16] Streptozotocin: IV, PO: Alkylates DNA.