Search results
Results from the WOW.Com Content Network
Clofazimine produces pink to brownish skin pigmentation in 75-100% of patients within a few weeks, as well as similar discoloration of most bodily fluids and secretions. These discolorations are reversible but may take months to years to disappear.
Pages in category "4-Chlorophenyl compounds" The following 200 pages are in this category, out of approximately 257 total. This list may not reflect recent changes .
Maleimide-mediated methodologies are among the most used in bioconjugation. [5] [6] Due to fast reactions and high selectivity towards cysteine residues in proteins, a large variety of maleimide heterobifunctional reagents are used for the preparation of targeted therapeutics, assemblies for studying proteins in their biological context, protein-based microarrays, or proteins immobilisation. [7]
MMAF is actually desmethyl-auristatin F; that is, the N-terminal amino group has only one methyl substituent instead of two as in auristatin F itself. [3] Structure of conjugate of MMAF with a monoclonal antibody (MAB). The attachment group consists of maleimide and caproic acid. About eight such structures are bound to a single antibody ...
Cyano-3-phenoxybenzyl (S)-2-(4-chlorophenyl)isovalerate. Cyano-3-phenoxybenzyl (S)-2-(4-chlorophenyl) ... C 25 H 22 Cl N O 3: Molar mass: 419.91 g·mol −1 Density:
4-Chlorophenol is an organic compound with the formula C 6 H 4 ClOH. It is one of three monochlorophenol isomers. It is a colorless or white solid that melts easily and exhibits significant solubility in water.
Due to the substituent effects on 4-chlorophenyl azide, acylation and alkylation would yield a major product that is newly substituted in the 3- and 5-positions on the aromatic ring. An example of this reaction is given below: Amine formation. Another application of 4-chlorophenyl azide is through the use of fungicides on plant pathogens. [4]
SR9009, also known as Stenabolic, is a research drug that was developed by professor Thomas Burris of the Scripps Research Institute as an agonist of Rev-ErbA (i.e., increases the constitutive repression of genes regulated by Rev-ErbA) [1] with a half-maximum inhibitory concentration (IC 50) = 670 nM for Rev-ErbAα and IC 50 = 800 nM for Rev-ErbAβ. [2]