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A popular over-the-counter decongestant ingredient doesn’t actually work, according to advisors to the FDA. CVS plans to pull some products containing popular decongestant from shelves.
An advisory committee to the FDA agreed this week that oral decongestant medications with phenylephrine are ineffective. Here is what we know about what does work. ... “A dried-up sinus is ...
Decongestant nasal sprays containing oxymetazoline may provide relief, but these medications should not be used for more than the recommended period. Longer use may cause rebound sinusitis . [ 75 ] It is unclear if nasal irrigation, antihistamines , or decongestants work in children with acute sinusitis. [ 76 ]
Xylometazoline is in the decongestant and alpha-adrenergic agonist families of medication. [5] [6] One study classified it with selectivity ratios in alpha 2 adrenergic receptors of 151 for a2A vs a2B, 4.5 a2A vs a2C, and 33.9 a2B vs a2C. Making it a highly selective a2A agonist. [7] Xylometazoline was patented in 1956 and came into medical use ...
Decongestant nasal sprays are advised for short-term use only, preferably 5 to 7 days at maximum. Some doctors advise to use them 3 days at maximum. A recent clinical trial has shown that a corticosteroid nasal spray may be useful in reversing this condition. [3] Topical nasal decongestants include: Oxymetazoline; Phenylephrine; Xylometazoline
Topical decongestants may also be helpful in reducing symptoms such as nasal congestion, but should not be used for long periods, as stopping them after protracted use can lead to a rebound nasal congestion called rhinitis medicamentosa. [citation needed]
CVS Health will remove from its shelves certain oral cough and cold products with phenylephrine as the only active ingredient, the U.S. pharmacy chain said on Thursday. A panel of advisers to the ...
Propylhexedrine should not be used if a MAOI has been used in the past 14 days or is currently in use by a person. [2] Unlike other topical decongestants, propylhexedrine is not required to carry a warning against use in individuals with hypertension. [9] Propylhexedrine is not recommended in individuals younger than six years of age. [10]