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An example is commissural disconnect in adults which usually results from surgical intervention, tumor, or interruption of the blood supply to the corpus callosum or the immediately adjacent structures. Callosal disconnection syndrome is characterized by left ideomotor apraxia and left-hand agraphia and/or tactile anomia, and is relatively rare.
Andermann syndrome, also known as agenesis of corpus callosum with neuronopathy (ACCPN), Charlevoix disease and KCC3 axonopathy among other names, [1] is a very rare neurodegenerative genetic disorder that damages the nerves used to control muscles and related to sensation and is often associated with agenesis of the corpus callosum. [1] [2] [3 ...
Split-brain or callosal syndrome is a type of disconnection syndrome when the corpus callosum connecting the two hemispheres of the brain is severed to some degree. It is an association of symptoms produced by disruption of, or interference with, the connection between the hemispheres of the brain.
Shapiro syndrome is an extremely rare disorder consisting of paroxysmal hypothermia (due to hypothalamic dysfunction of thermoregulation), hyperhydrosis (sweating), and agenesis of the corpus callosum with onset typically in adulthood. The disease affects about 50-60 people worldwide.
Deep gray matter involvement commonly occurs in ADEM but is very rare in MS. Leptomeningeal involvement is not typical of either MS or ADEM: if 10 lesions are found in the brain of an MS patient, a lesion may be found in the corpus callosum. If a Susac patient has 10 lesions, more than half will be in the corpus callosum.
Anterior cerebral artery syndrome is a condition whereby the blood supply from the anterior cerebral artery (ACA) is restricted, leading to a reduction of the function of the portions of the brain supplied by that vessel: the medial aspects of the frontal and parietal lobes, basal ganglia, anterior fornix and anterior corpus callosum.
Some patients do not show most of the symptoms related to colpocephaly, such as psychomotor abnormalities and agenesis of the corpus callosum. In some cases, signs appear later on in life and a significant number of children only develop minor disabilities. The following list includes common symptoms of colpocephaly. [3] [4] [5]
Individuals with this condition usually have the following symptoms: [1] One-sided coronal craniosynostosis; Multiple suture synostosis; Agenesis of the corpus callosum that can either be complete or partial; Polysyndactyly, preaxial type; Hand/foot syndactyly; Pearl-white areas in the skin that are prone to scarring and suffer from atrophy