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Alkaline citrates are used to prevent recurrent calcium stone formation. [13] [14] [15] [5] This is one of the major types of kidney stones. [16] [17] The citrate salts can increase urine citrate, which binds with urine calcium, reduces supersaturation of calcium salts, and inhibits crystal formation. [18] [8] This helps prevent kidney stones ...
Historically, the medical application of alkaline diets largely focused on preventing recurrence of kidney stones as well as the prevention of recurrent urinary tract infections, by relying on the recognized ability of such diets to affect urinary pH. Years ago, such a diet was used to adjust the acidity of the urinary environment that the ...
Increasing the amount of citrate in the blood is also important for kidney stone prevention because citrate creates chemical complexes with calcium, preventing nucleation and agglomeration with oxalate that leads to kidney stones. [2] Because of these two mechanisms of treatment, it can be used to treat both calcium oxalate and uric acid kidney ...
Kidney stones are primarily composed of calcium salts, with the most common being calcium oxalate (70-80%), followed by calcium phosphate and uric acid. When urine contains high concentrations of these ions, they can form crystals and eventually stones. [41] The formation of kidney stones occurs in three main phases: [41]
There are over 1 million nephrons in each kidney; these nephrons act as filters inside the kidneys. The kidneys filter needed materials and waste. Needed materials go back into the bloodstream; unneeded materials become urine and are expelled through the urethra. In some cases, excess wastes crystallize as kidney stones.
A number of important medical conditions are caused by stones: [citation needed] Nephrolithiasis (kidney stones) Can cause hydronephrosis (swollen kidneys) and kidney failure; Can predispose to pyelonephritis (kidney infections) Can progress to urolithiasis; Urolithiasis (urinary bladder stones) Can progress to bladder outlet obstruction
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