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In this syndrome, decreased sensation and loss of reflexes occur first in the toes on each foot, then extend upward. It is usually described as a glove-stocking distribution of numbness, sensory loss, dysesthesia and nighttime pain. The pain can feel like burning, pricking sensation, achy or dull.
Polyneuropathy (from Greek poly- 'many' neuro- 'nerve' and -pathy 'sickness') is damage or disease affecting peripheral nerves (peripheral neuropathy) in roughly the same areas on both sides of the body, featuring weakness, numbness, and burning pain. [1]
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Peripheral neuropathy is associated with a sensory loss in a "glove and stocking" distribution that begins at the peripheral and slowly progresses upwards, and may also be associated with acute and chronic pain. Peripheral neuropathy is not just limited to the somatosensory nerves, but the autonomic nervous system too (autonomic neuropathy). [8]
The distribution and severity of the disease depends on regional dietary habits, individual drinking habits, as well as an individual's genetics. [12] Large studies have been conducted and show that alcoholic polyneuropathy severity and incidence correlates best with the total lifetime consumption of alcohol.
Paclitaxel binds to tubulin and stabilizes the microtubules which leads to inhibition of cell division. Paclitaxel is provided intravenously, with a dose limiting toxicity of peripheral neuropathy. Peripheral sensory neuropathy presents with numbness and tingling in a stocking-and-glove distribution, which may disturb daily function of the ...
Each glove can be used any number of times, but the same side of one glove cannot be exposed to more than one person. Gloves can be re-used any number of times, and more than one can be used simultaneously. Given M doctors and N patients, the minimum number of gloves G(M, N) required for all the doctors to examine all the patients is given by:
Toe socks (also known as fingersocks, glove socks, 5-toe socks or digital socks) are socks that have been knitted so that each toe is individually encased the same way as fingers within a glove. All sock lengths are available as toe socks, from no-show style to anklet and ankle socks through to knee-high and over-knee socks.
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