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While knowledge was being accumulated regarding the biology of phages and how to use phage cocktails correctly, early uses of phage therapy were often unreliable. [29] Since the early 20th century, research into the development of viable therapeutic antibiotics had also been underway, and by 1942, the antibiotic penicillin G had been ...
George Eliava pioneered the use of phages in treating bacterial infections. Phages were discovered to be antibacterial agents and were used in the former Soviet Republic of Georgia (pioneered there by Giorgi Eliava with help from the co-discoverer of bacteriophages, Félix d'Hérelle) during the 1920s and 1930s for treating bacterial infections.
The isolation of phages by d'Herelle works like this: Nutritional medium is infected with bacteria; the medium turns opaque. The bacteria are infected with phages and die, producing new phages; the medium clears. The medium is filtered through porcelain filter, holding back bacteria and larger objects; only the smaller phages pass through.
This list of wars by death toll includes all deaths directly or indirectly caused by the deadliest wars in history. These numbers encompass the deaths of military personnel resulting directly from battles or other wartime actions, as well as wartime or war-related civilian deaths, often caused by war-induced epidemics, famines, or genocides.
The ensuing Black Death may have killed up to 25 million total, including China and roughly a third of the population of Europe and in the next decades, changing the course of Asian and European history. Biologicals were extensively used in many parts of Africa from the sixteenth century AD, most of the time in the form of poisoned arrows, or ...
World War II began in Europe on 1 September 1939 [1] [2] with the German invasion of Poland and the United Kingdom and France's declaration of war on Germany two days later on 3 September 1939. Dates for the beginning of the Pacific War include the start of the Second Sino-Japanese War on 7 July 1937, [ 3 ] [ 4 ] or the earlier Japanese ...
German-occupied Europe (or Nazi-occupied Europe) refers to the sovereign countries of Europe which were wholly or partly militarily occupied and civil-occupied, including puppet governments, by the military forces and the government of Nazi Germany at various times between 1939 and 1945, during World War II, administered by the Nazi regime under the dictatorship of Adolf Hitler.
About 1.2 million Austrians served in all branches of the German armed forces during World War II. After the defeat of the Axis Powers, the Allies occupied Austria in four occupation zones set up at the end of World War II until 1955, when the country again became a fully independent republic under the condition that it remained neutral.