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  2. Guidelines say more women may need breast cancer gene test - AOL

    www.aol.com/news/2019-08-26-guidelines-say-more...

    Most cancer isn't caused by BRCA mutations — they account for 5 percent to 10 percent of breast cancers and 15 percent of ovarian cancers — so the gene tests aren't for everyone. But mutations ...

  3. BRCA mutation - Wikipedia

    en.wikipedia.org/wiki/BRCA_mutation

    BRCA-related breast cancer appears at an earlier age than sporadic breast cancer. [9]: 89–111 It has been asserted that BRCA-related breast cancer is more aggressive than normal breast cancer, however most studies in specific populations suggest little or no difference in survival rates despite seemingly worse prognostic factors. [11] [12] [13]

  4. Can 23andMe Detect the BRCA Gene? What To Know Before Testing

    www.aol.com/news/23andme-detect-brca-gene-know...

    Home genetic test kits from 23andMe may detect some important BRCA gene mutations that can increase your risk for breast cancer. Here's what to know before you test.

  5. BRCA2 - Wikipedia

    en.wikipedia.org/wiki/BRCA2

    A patent application for the isolated BRCA1 gene and cancer-cancer promoting mutations, as well as methods to diagnose the likelihood of getting breast cancer, was filed by the University of Utah, National Institute of Environmental Health Sciences (NIEHS) and Myriad Genetics in 1994; [42] over the next year, Myriad, in collaboration with other ...

  6. HRDetect - Wikipedia

    en.wikipedia.org/wiki/HRDetect

    Cohort of 80 Breast Cancer Samples HRDetect was tested in 80 breast cancer cases with mainly ER positive and HER2 negative. The tool was able to find ones that exceed HRDetect score 0.7, including one germline BRCA1 mutation carrier, four germline BRCA2 mutation carriers and one somatic BRCA2 mutation carrier.

  7. Hereditary breast–ovarian cancer syndrome - Wikipedia

    en.wikipedia.org/wiki/Hereditary_breast–ovarian...

    Absolute risk of cancers in BRCA1 or BRCA2 mutation. [4]A number of genes are associated with HBOC. [5] The most common of the known causes of HBOC are: BRCA mutations: [5] Harmful mutations in the BRCA1 and BRCA2 genes can produce very high rates of breast and ovarian cancer, as well as increased rates of other cancers.

  8. List of breast cancer cell lines - Wikipedia

    en.wikipedia.org/wiki/List_of_breast_cancer_cell...

    Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease. Experiments using cell culture are used for developing new diagnostic tests and new treatments for diseases. This is a list of major breast cancer cell lines that are primarily used in breast cancer ...

  9. Myriad Genetics - Wikipedia

    en.wikipedia.org/wiki/Myriad_Genetics

    Myriad Genetics, Inc. is an American genetic testing and precision medicine company based in Salt Lake City, Utah, United States.Myriad employs a number of proprietary technologies that permit doctors and patients to understand the genetic basis of human disease and the role that genes play in the onset, progression and treatment of disease.

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