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The appendicular skeleton, comprising the arms and legs, including the shoulder and pelvic girdles, contains 126 bones, bringing the total for the entire skeleton to 206 bones. Infants are born with about 270 bones [ 4 ] with most of it being cartilage, but will later fuse together and decrease over time to 206 bones.
Endochondral ossification is responsible for development of most bones including long and short bones, [4] the bones of the axial (ribs and vertebrae) and the appendicular skeleton (e.g. upper and lower limbs), [5] the bones of the skull base (including the ethmoid and sphenoid bones) [6] and the medial end of the clavicle. [7]
A bone is a rigid organ [1] that constitutes part of the skeleton in most vertebrate animals. Bones protect the various other organs of the body, produce red and white blood cells, store minerals, provide structure and support for the body, and enable mobility.
Each osteon consists of concentric layers, or lamellae, of compact bone tissue that surround a central canal, the Haversian canal. The Haversian canal contains the bone's blood supplies. The boundary of an osteon is the cement line. Each Haversian canal is surrounded by varying number (5-20) of concentrically arranged lamellae of bone matrix.
Components that are essential for osteoblast bone formation include mesenchymal stem cells (osteoblast precursor) and blood vessels that supply oxygen and nutrients for bone formation. Bone is a highly vascular tissue, and active formation of blood vessel cells, also from mesenchymal stem cells, is essential to support the metabolic activity of ...
A true endoskeleton is derived from mesodermal tissue. In three phyla of animals, Chordata, Echinodermata and Porifera (), endoskeletons of various complexity are found.An endoskeleton may function purely for structural support (as in the case of Porifera), but often also serves as an attachment site for muscles and a mechanism for transmitting muscular forces as in chordates and echinoderms ...
Thus the metaphysis contains a highly metabolic set of tissues including trabecular (spongy) bone, blood vessels, as well as marrow adipose tissue (MAT). The metaphysis may be divided anatomically into three components based on tissue content: a cartilaginous component ( epiphyseal plate ), a bony component (metaphysis) and a fibrous component ...