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Using these techniques Nicholson showed that solute and water movement through the brain parenchyma slows as the extracellular volume fraction decreases and becomes more tortuous. [ 27 ] As an alternative explanation to diffusion, Cserr and colleagues proposed that convective bulk flow of interstitial fluid from the brain parenchyma to the CSF ...
Viral encephalitis is inflammation of the brain parenchyma, called encephalitis, by a virus.The different forms of viral encephalitis are called viral encephalitides. It is the most common type of encephalitis and often occurs with viral meningitis.
The striatum (pl.: striata) or corpus striatum [5] is a cluster of interconnected nuclei that make up the largest structure of the subcortical basal ganglia. [6] The striatum is a critical component of the motor and reward systems; receives glutamatergic and dopaminergic inputs from different sources; and serves as the primary input to the rest of the basal ganglia.
Once the immune cells have reached the CNS parenchyma and the immune attack is underway, the CNS parenchymal cells are sacrificed in order to battle the infection. The autoimmune response to EAE leads to chronic attack of oligodendrocytes and neurons, which promotes demyelination and axonal loss. This can ultimately result in the loss of CNS ...
Brain Aβ is elevated in people with sporadic Alzheimer's disease. Aβ is the main constituent of brain parenchymal and vascular amyloid; it contributes to cerebrovascular lesions and is neurotoxic. [33] [34] [35] It is unresolved how Aβ accumulates in the central nervous system and subsequently initiates the disease of cells. Significant ...
Lung parenchyma showing damage due to large subpleural bullae. Parenchyma (/ p ə ˈ r ɛ ŋ k ɪ m ə /) [1] [2] is the bulk of functional substance in an animal organ or structure such as a tumour. In zoology, it is the tissue that fills the interior of flatworms. In botany, it is some layers in the cross-section of the leaf. [3]
The cisterna magna (posterior cerebellomedullary cistern, [1] or cerebellomedullary cistern [2] [3]) is the largest of the subarachnoid cisterns.It occupies the space created by the angle between the caudal/inferior surface of the cerebellum, and the dorsal/posterior surface of the medulla oblongata (it is created by the arachnoidea that bridges this angle [3]).
This is critical because the brain lacks a true lymphatic system. In the remainder of the body, small amounts of protein are able to leak from the parenchymal capillaries through the lymphatic system. In the brain, this ends up in the interstitial space. The protein portions are able to leave through the very permeable pia mater and enter the ...