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The coronavirus RNA genome has a 5′ methylated cap and a 3′ polyadenylated tail, which allows it to act like a messenger RNA and be directly translated by the host cell's ribosomes. The host ribosomes translate the initial overlapping open reading frames ORF1a and ORF1b of the virus genome into two large overlapping polyproteins, pp1a and ...
The WHO ended the PHEIC for COVID-19 on 5 May 2023. [4] The disease has continued to circulate, but as of 2024, experts were uncertain as to whether it was still a pandemic. [11] [12] Pandemics and their ends are not well-defined, and whether or not one has ended differs according to the definition used.
SARS-CoV-2 is the seventh known coronavirus to infect people, after 229E, NL63, OC43, HKU1, MERS-CoV, and the original SARS-CoV. [105] Like the SARS-related coronavirus implicated in the 2003 SARS outbreak, SARS‑CoV‑2 is a member of the subgenus Sarbecovirus (beta-CoV lineage B). [106] [107] Coronaviruses undergo frequent recombination. [108]
A generic coronavirus illustration. Coronavirus diseases are a family of usually mild illnesses in humans, including those such as the common cold, that have resulted in outbreaks and pandemics such as the 1889-1890 pandemic, [118] [119] the 2002–2004 SARS outbreak, Middle East respiratory syndrome–related coronavirus and the COVID-19 pandemic.
5 March: The majority of learners affected by COVID-19 emergency measures were located in China, with 233 million learners affected, followed by Japan at 16.5 million and Iran at 14.5 million. [ 83 ] 10 March: One in five students worldwide was "staying away from school due to the COVID-19 crisis" while another one in four was barred from ...
The transmission of COVID-19 is the passing of coronavirus disease 2019 from person to person. COVID-19 is mainly transmitted when people breathe in air contaminated by droplets/aerosols and small airborne particles containing the virus. Infected people exhale those particles as they breathe, talk, cough, sneeze, or sing.
As of 2023, the COVID-19 pandemic is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV‑2). Its impact has been broad, affecting general society, the global economy, culture, ecology, politics, and other areas.
A term for COVID-19 used by former United States president Donald Trump to emphasize that the pandemic started in China. Comirnaty. Main article: Comirnaty. The commercial name for the FDA approved COVID-19 vaccine from Pfizer, released August 21, 2021. It also has several other names or designators used on the actual vials. Community transmission