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Simplified control circuit of human thermoregulation. [8]The core temperature of a human is regulated and stabilized primarily by the hypothalamus, a region of the brain linking the endocrine system to the nervous system, [9] and more specifically by the anterior hypothalamic nucleus and the adjacent preoptic area regions of the hypothalamus.
Magnesium (12 Mg) naturally occurs in three stable isotopes: 24 Mg, 25 Mg, and 26 Mg. There are 19 radioisotopes that have been discovered, ranging from 18 Mg to 40 Mg (with the exception of 39 Mg). The longest-lived radioisotope is 28 Mg with a half-life of 20.915(9) h.
This isotope has a relatively short half-life (21 hours) and its use was limited by shipping times. The nuclide 26 Mg has found application in isotopic geology, similar to that of aluminium. 26 Mg is a radiogenic daughter product of 26 Al, which has a half-life of 717,000 years. Excessive quantities of stable 26
Polonium in the body has a biological half-life of about 30 to 50 days. Caesium in the body has a biological half-life of about one to four months. Mercury (as methylmercury) in the body has a half-life of about 65 days. Lead in the blood has a half life of 28–36 days. [29] [30] Lead in bone has a biological half-life of about ten years.
Magnesium orotate may be used as adjuvant therapy in patients on optimal treatment for severe congestive heart failure, increasing survival rate and improving clinical symptoms and patient's quality of life. [11] In 2022, magnesium salts were the 207th most commonly prescribed medication in the United States, with more than 1 million prescriptions.
An individual's body temperature typically changes by about 0.5 °C (0.9 °F) between its highest and lowest points each day. [15] Body temperature is sensitive to many hormones, so women have a temperature rhythm that varies with the menstrual cycle, called a circamensal rhythm. [11] [unreliable medical source?
The saline cools the person's whole body by lowering the temperature of a person's blood. Catheters reduce temperature at rates ranging from 1.5 to 2 °C (2.7 to 3.6 °F) per hour. Through the use of the control unit, catheters can bring body temperature to within 0.1 °C (0.18 °F) of the target level.
Treatment involves stopping the magnesium a person is getting. [2] Treatment when levels are very high include calcium chloride, intravenous normal saline with furosemide, and hemodialysis. [1] Hypermagnesemia is uncommon. [3] Rates among hospitalized patients in renal failure may be as high as 10%. [2]