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However, salivary tumors show a great deal of morphological diversity, as well as variations in the nature of the lesion (malignant vs. benign): approximately 20% to 25% of parotid tumors, 35% to 40% of submandibular tumors, and more than 90% of sublingual gland tumors are malignant. [8]
Stafne defect is uncommon, [6] and has been reported to develop anywhere between the ages of 11 and 30 years old, [12] (although the defect is developmental, it does not seem to be present from birth, implying that the lesion develops at a later age). [5] Usually the defect is unilateral (on one side only) and most commonly occurs in men.
Around 50% of the tumours found in the submandibular glands are benign. Sublingual gland tumours are very rare but if present, they are most likely to be malignant. [3] [18] Saku et al. in 1997 [19] and Venturi [20] [21] in 2021, reported the causal role for ionizing radiation in salivary gland tumorigenesis, particularly for mucoepidermoid ...
The most common causes of enlargement of the submandibular lymph nodes are infections of the head, neck, ears, eyes, nasal sinuses, pharynx, and scalp. [1] The lymph glands may be affected by metastatic spread of cancers of the oral cavity, anterior portion of the nasal cavity, soft tissues of the mid-face, and submandibular salivary gland. [1]
A study done on the epidemiology of sialadenitis in the United States of America found that acute suppurative parotitis is responsible for 0.01–0.02% of hospital admissions, with the submandibular gland accounting for 10% of cases of sialadenitis in the major salivary glands in this population. [1]
Rarely, removal of the submandibular gland may become necessary in cases of recurrent stone formation. Sialolithiasis is common, accounting for about 50% of all disease occurring in the major salivary glands and causing symptoms in about 0.45% of the general population. Persons aged 30–60 and males are more likely to develop sialolithiasis. [2]
[10] [14] Periapical abscesses of these teeth also result in lingual cortical penetration, leading to submandibular infection. [ 10 ] Other causes such as oral ulcerations, infections secondary to oral malignancy, mandible fractures, sialolithiasis-related submandibular gland infections, [ 10 ] and penetrating injuries of the mouth floor [ 15 ...
The most common cause of enlargement of the submental lymph nodes are infections (including viral infections (mononucleosis, Epstein-Barr virus infection, and cytomegaloviral infections), toxoplasmosis, and dental infections (e.g. periodontitis)).