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7-Hydroxymitragynine (7-OH) is a terpenoid indole alkaloid from the plant Mitragyna speciosa, commonly known as kratom. [2] It was first described in 1994 [3] and is a human metabolite metabolized from mitragynine present in the Mitragyna speciosa. 7-OH binds to opioid receptors like mitragynine, but research suggests that 7-OH binds with greater efficacy.
In Thai varieties of kratom, mitragynine is the most abundant component (up to 66% of total alkaloids), while 7-hydroxymitragynine (7-OH) is a minor constituent (up to 2% of total alkaloid content). In Malaysian kratom varieties, mitragynine is present at lower concentration (12% of total alkaloids). [5]
A sign advertising the sale of Kratom is pictured outside the Conoco gas station at the corner of Gilbert and Benton streets Tuesday, Oct. 1, 2024 in Iowa City, Iowa.
This is an accepted version of this page This is the latest accepted revision, reviewed on 26 February 2025. Plant species, recreational drug (kratom) Mitragyna speciosa Conservation status Least Concern (IUCN 3.1) Scientific classification Kingdom: Plantae Clade: Tracheophytes Clade: Angiosperms Clade: Eudicots Clade: Asterids Order: Gentianales Family: Rubiaceae Genus: Mitragyna Species: M ...
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US FDA warns online vendors selling unapproved weight-loss drugs. December 17, 2024 at 5:29 PM (Reuters) - The U.S. Food and Drug Administration said on Tuesday it has sent warning letters to four ...
On August 22, 1975, Governor James Rhodes signed a bill decriminalizing cannabis, making Ohio the sixth state to do so. [2] Under Ohio law, the possession of up to 100 grams (3½ oz) of marijuana is a "minor misdemeanor" which carries a maximum fine of $150. Possession of more than 100 grams (3½ oz) but less than 200 grams (7 oz) of marijuana ...
According to the National Conference of State Legislatures, several other states also considered legislation, including New Jersey, New York, Florida, and Ohio. [178] Illinois passed a law on July 27, 2010, banning all synthetic cannabinoids as of January 1, 2011. [182]