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Plasmapheresis (from the Greek πλάσμα, plasma, something molded, and ἀφαίρεσις aphairesis, taking away) is the removal, treatment, and return or exchange of blood plasma or components thereof from and to the blood circulation. It is thus an extracorporeal therapy, a medical procedure performed outside the body. [1]
In medicine, photopheresis (aka extracorporeal photopheresis or ECP) [1] is a form of apheresis and photodynamic therapy in which blood is subject to apheresis to separate buffy coat (WBC + platelets) from whole blood, chemically treated with 8-methoxypsoralen (instilled into a collection bag or given per os in advance), exposed to ultraviolet light (UVA), and then returned to the patient. [2]
Plasmapheresis is a medical therapy that involves blood plasma extraction, treatment, ... which decreases the preparation cost of the samples relative to plasma samples.
Apheresis (ἀφαίρεσις (aphairesis, "a taking away")) is a medical technology in which the blood of a person is passed through an apparatus that separates out one particular constituent and returns the remainder to the circulation.
The usage of immunoadsorption as medical procedure is still limited in some countries of the world, especially in Northern America. The additional costs for immunoadsorption are balanced by the reduced length of stay time as well as the reduced need of plasma substituting solutions and handling of side effects. [9]
Exchange transfusion has been used for the treatment of severe malaria in the past. [ 11 ] [ 12 ] However, in 2013 the CDC examined the limited evidence available and found no evidence that exchange transfusion has any beneficial effects (decreased mortality) in people with very high parasite loads (> 10%). [ 12 ]
Almost all plasmapheresis in the US is performed by ... Journal that in 1991 one treatment of Cerezyme for one ... Assessment cerezyme cost $1.90 per unit ...
In reaction, convalescent blood plasma was considered as a possibility and is used as a treatment option at least for severe cases. [ 10 ] [ 11 ] [ 12 ] In May 2021, India was one of the first major country to remove plasma from its national COVID-19 guidelines.