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  2. Urease - Wikipedia

    en.wikipedia.org/wiki/Urease

    Urea is found naturally in the environment and is also artificially introduced, comprising more than half of all synthetic nitrogen fertilizers used globally. [26] Heavy use of urea is thought to promote eutrophication , despite the observation that urea is rapidly transformed by microbial ureases, and thus usually does not persist. [ 27 ]

  3. Timeline of peptic ulcer disease and Helicobacter pylori

    en.wikipedia.org/wiki/Timeline_of_peptic_ulcer...

    Urease 1924 Luck and Seth discover urease in the human stomach, which they believe is naturally occurring. [11] 1925 Hoffman injects a small sample from a human with PUD into a guinea pig, producing ulcers, and isolates a bacterium which he believes caused the ulcers. [12] 1936

  4. Helicobacter pylori - Wikipedia

    en.wikipedia.org/wiki/Helicobacter_pylori

    Prolonged bleeding may cause anemia leading to weakness and fatigue. Inflammation of the pyloric antrum, which connects the stomach to the duodenum, is more likely to lead to duodenal ulcers, while inflammation of the corpus may lead to a gastric ulcer. Stomach cancer can cause nausea, vomiting, diarrhoea, constipation, and unexplained weight ...

  5. Helicobacter - Wikipedia

    en.wikipedia.org/wiki/Helicobacter

    Helicobacter heilmannii sensu lato (i.e. H. heilmanni s.l.) is a grouping of non-H. pylori Helicobacter species that take as part of their definition a similarity to H. pylori in being associated with the development of stomach inflammation, stomach ulcers, [11] duodenum ulcers, [12] stomach cancers that are not lymphomas, and extranodal ...

  6. Virulence - Wikipedia

    en.wikipedia.org/wiki/Virulence

    Helicobacter pylori is able to survive in the acidic environment of the human stomach by producing the enzyme urease. Colonization of the stomach lining by this bacterium can lead to gastric ulcers and cancer. The virulence of various strains of Helicobacter pylori tends to correlate with the level of production of urease. [citation needed ...

  7. Urea - Wikipedia

    en.wikipedia.org/wiki/Urea

    Urea labeled with carbon-14 or carbon-13 is used in the urea breath test, which is used to detect the presence of the bacterium Helicobacter pylori (H. pylori) in the stomach and duodenum of humans, associated with peptic ulcers. The test detects the characteristic enzyme urease, produced by H. pylori, by a reaction that produces ammonia from ...

  8. Rapid urease test - Wikipedia

    en.wikipedia.org/wiki/Rapid_urease_test

    Rapid urease test, also known as the CLO test (Campylobacter-like organism test), is a rapid diagnostic test for diagnosis of Helicobacter pylori. [1] The basis of the test is the ability of H. pylori to secrete the urease enzyme, which catalyzes the conversion of urea to ammonia and carbon dioxide .

  9. Stomach disease - Wikipedia

    en.wikipedia.org/wiki/Stomach_disease

    The most common cause of gastroparesis is diabetes but it can also occur from a blockage at the distal end of stomach, a cancer or a stroke. Symptoms of gastroparesis includes abdominal pain, fullness, bloating, nausea, vomiting after eating food, loss of appetite and feeling of fullness after eating small amounts of food.