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Hypertriglyceridemia is the presence of high amounts of triglycerides in the blood.Triglycerides are the most abundant fatty molecule in most organisms. Hypertriglyceridemia occurs in various physiologic conditions and in various diseases, and high triglyceride levels are associated with atherosclerosis, even in the absence of hypercholesterolemia (high cholesterol levels) and predispose to ...
High triglyceride levels can cause lipemia retinalis, a condition in which the veins and arteries in your eye become discolored, turning a creamy white or red color. You might notice blurred ...
Overexpression of SREBP-1a or SREBP-1c in mouse liver cells results in the build-up of hepatic triglycerides and higher expression levels of lipogenic genes. [17] Lipogenic gene expression in the liver via glucose and insulin is moderated by SREBP-1. [18]
They found that a build-up of triglyceride levels led to nonalcoholic fatty liver disease. This was due to HL's inability to convert the triacylglycerides in IDL, and thereby creating LDL. Thus, the inability of endothelial cells to take up free fatty acids becomes higher and more IDL gets stored in the liver.
Liver cancer. High blood pressure. Type 2 diabetes. Cardiovascular disease. ... Having high cholesterol or triglycerides. Metabolic syndrome. Rapid weight loss. Infections like hepatitis C.
Lipids are stored in white adipose tissue as triglycerides. In a lean young adult human, the mass of triglycerides stored represents about 10–20 kilograms. Triglycerides are formed from a backbone of glycerol with three fatty acids. Free fatty acids are activated into acyl-CoA and esterified to finally reach the triglyceride droplet.
Triglycerides are the main constituents of body fat in humans and other vertebrates as well as vegetable fat. [2] They are also present in the blood to enable the bidirectional transference of adipose fat and blood glucose from the liver and are a major component of human skin oils. [3] Many types of triglycerides exist.
Liver cancer. High blood pressure. Type 2 diabetes. Cardiovascular disease. ... Having high cholesterol or triglycerides. Metabolic syndrome. Rapid weight loss. Infections like hepatitis C.
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